Emerging concepts in heart failure management and treatment

Guest Editor: Edgardo Kaplinsky, Cardiology Unit, Hospital Municipal de Badalona, Badalona Spain; Barcelona University, Barcelona, Spain

Heart failure is probably the area of cardiology that has grown the most in recent years with a likely turning point being, for example, the publication of results of the PARADIGM-HF study (Angiotensin-Neprilysin Inhibition versus Enalapril in Heart Failure) in 2014, which is the largest study conducted to date in heart failure (8842 patients). For […]

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Hospital pharmacy, rational use of medicines and patient safety in Latin America

Guest Editor: Fela Viso Gurovich, Private Consulting, Pachuca de Soto, Hidalgo, Mexico

Public and private hospitals around the world, and specifically in Latin America, have the necessity to diminish medicine costs, support their rational use and achieve patient safety. Nowadays, an important competent strategy to fulfil these goals is the implementation of different pharmaceutical services considering the characteristics and objectives of each hospital. All pharmaceutical services are […]

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Treatment of advanced non-small-cell lung cancer: one size does not fit all

Guest Editors: Andrea De Giglio, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy; Giulio Metro, Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Italy; Biagio Ricciuti, Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston, MA, USA

In recent years, advanced non-small-cell lung cancer has undergone tremendous progress in its management. On the one hand, the use of immune checkpoints inhibitors (anti-PD-(L)1 and anti-CTLA4) with or without chemotherapy has revolutionized the prognosis of a relevant number of patients; on the other hand, the discovery of several actionable genetic drivers in adenocarcinoma histology, […]

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Tackling clinical complexity in breast cancer

Guest Editor: Federico Sottotetti, Operative Unit of Medical Oncology, IRCCS-ICS Maugeri, Pavia, Italy

Breast cancer, one of the most common malignancies worldwide, is an example of complex disease. Clinical complexity is an increasingly recognized feature of internal medicine and oncology patients, who are often characterized by multifaceted needs determined by both biological (i.e. intrinsic to patient or disease biology) and non-biological (i.e. socioeconomic, cultural, environmental and behavioural) factors. […]

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