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Women’s health

Advances in the use of PARP inhibitor therapy for breast cancer

Authors: Kelly E McCann MD, PhD, Sara A Hurvitz MD

In the care of oncology patients, poly-ADP-ribose polymerase (PARP) inhibitors are best known as a semitargeted treatment
for BRCA1- and BRCA2-associated ovarian and breast cancers, this article reviews the broader understanding of PARP biology that has spurred interest in expanding their clinical utility.

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Metformin in the management of diabetes during pregnancy and lactation

Authors: Gagan Priya MD, DM, Sanjay Kalra MD, DM

This review explores the current place of metformin in the management of gestational diabetes and type 2 diabetes during pregnancy and lactation.

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Needs and preferences of women users of oral contraceptives in selected countries in Central and Eastern Europe

Authors: Tomas Fait, Dmitry Buryak, Monica-Mihaela Cirstoiu, Eva Luczai, Rafal Janczura

This study comprises a survey of current users of oral contraceptives to define and confirm areas of specific needs, and to gain insight into their views and preferences for oral contraceptive formulations.

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Prognostic and predictive factors of eribulin efficacy in heavily pretreated patients affected by metastatic breast cancer: correlation with tumor biology and previous therapies

Authors: Sabrina Rossi, Alessandra Cassano, Antonia Strippoli, Giovanni Schinzari, Ettore D’Argento, Michele Basso, Carlo Barone

This retrospective study looks to find specific predictive criteria related to patient or tumor characteristics in order to select patients that might benefit the most from eribulin and define the correct treatment sequence.

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