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Neurology

From medications to surgery: advances in the treatment of motor complications in Parkinson’s disease

Authors: Kanae Jennifer Nagao MBBS (Hons), FRACP, Neepa J Patel MD

This review provides an overview of the pharmacologic and surgical therapies currently available and under investigation for the treatment of motor fluctuations and dyskinesia in Parkinson’s disease.

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Mitochondrial disorders and drugs: what every physician should know

Authors: Daniele Orsucci MD, Elena Caldarazzo Ienco MD, Gabriele Siciliano MD, PhD, Michelangelo Mancuso MD, PhD

Keywords: coenzyme Q10, drugs, mitochondria, mtDNA, mitochondrial diseases, toxicity Citation: Orsucci D, Caldarazzo Ienco E, Siciliano G, Mancuso M. Mitochondrial disorders and drugs: what every physician should know. Drugs in Context 2019; 8: 212588. DOI: 10.7573/dic.212588 Contributions: All authors contributed

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Use of botulinum toxin for movement disorders

Authors: Carlos Henrique Ferreira Camargo MD, MSc, PhD, Hélio Afonso Ghizoni Teive MD, MSc, PhD

The aim of this review is to present the new and well-established uses of botulinum toxin for movement disorders.

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Therapy of episodic ataxias: case report and review of the literature

Authors: Daniele Orsucci MD, Laura Maria Raglione MD, Monica Mazzoni MD, Marco Vista MD

This paper presents
an illustrative case report followed by a perspective review of genetic ataxias.

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The therapeutic role of minocycline in Parkinson’s disease

Authors: Seyda Cankaya MD, Baris Cankaya MD, Ulkan Kilic PhD, Ertugrul Kilic PhD, Burak Yulug MD

This review summarizes the preclinical and clinical findings suggesting the neuroprotective role of minocycline in Parkinson’s disease.

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