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Neurology

Therapy of episodic ataxias: case report and review of the literature

Authors: Daniele Orsucci MD, Laura Maria Raglione MD, Monica Mazzoni MD, Marco Vista MD

This paper presents
an illustrative case report followed by a perspective review of genetic ataxias.

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The therapeutic role of minocycline in Parkinson’s disease

Authors: Seyda Cankaya MD, Baris Cankaya MD, Ulkan Kilic PhD, Ertugrul Kilic PhD, Burak Yulug MD

This review summarizes the preclinical and clinical findings suggesting the neuroprotective role of minocycline in Parkinson’s disease.

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Febrile seizures: an overview

Authors: Alexander KC Leung MBBS, FRCPC, FRCP (UK and Irel), FRCPCH, FAAP, Kam Lun Hon MD, FAAP, FCCM, Theresa NH Leung MBBS, FRCPCH, FHKAM (Paed)

This review provides an update on the current understanding, evaluation, and management of febrile seizures.

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Tardive dyskinesia in patients treated with atypical antipsychotics: case series and brief review of etiologic and treatment considerations

Authors: Jungjin Kim, Eric MacMaster, Thomas L Schwartz

Tardive dyskinesia (TD) can be a disfiguring side-effect of antipsychotic medications. In this article the authors review the risk of TD, the potential etiologic mechanisms and present some interesting cases of patients taking atypical antipsychotics who developed TD.

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Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon

Authors: Thomas L Schwartz, Viral Goradia

In this article, the authors explore basic sleep physiology, the mechanism of action for each class of hypnotic drugs and their clinical application. The potential pharmacologic sleep-inducing mechanisms of future hypnotics are also described and discussed.

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