Articles - Drugs in Context

Rapid Efficacy of riSankizumab in pretibial psoriasis invOLVEment: RESOLVE

Nicoletta Bernardini, Nevena Skroza, Laura Atzori, Cristina Mugheddu, Matteo Megna, Sara Cacciapuoti, Michela Ortoncelli, Maria A Montesu, Antonio Carpentieri, Martino Carriero, Maria G Atzori, Gianmario Addis, Riccardo Balestri, Giulia Rech, Pierluigi Bruni, Manuela Papini, Concetta Potenza

Article Type

Original Research

Published

05 Sep 2024

This multicentre study focuses on psoriasis affecting sensitive areas, its impact on quality of life and the therapeutic response to risankizumab.

RNA interference therapy in cardiology: will new targets improve therapeutic goals?

Renata TJ Fazoli, Luciano F Drager, Roberto Kalil-Filho, Giuliano Generoso

Article Type

Review

Published

20 Aug 2024

This review highlights the historical timeline of the development of siRNA-based drugs, their clinical indications, potential side-effects and future perspectives.

Risk of gastrointestinal bleeding in Asian patients receiving oral anticoagulants for stroke prevention in atrial fibrillation

Alejandro Bimbo Diaz, Jeremy Chow, Fan Kee Hoo, Gary Lee Chin Keong, Narayanaswamy Venketasubramanian, Nannette Rey, Gregorio Rogelio, Radhika Mehta

Article Type

Meeting Report

Published

13 Aug 2024

The Menarini Asia Pacific Advancing Patient care with EdoXaban (APEX) 2023 Expert Meeting convened in Kuala Lumpur, Malaysia, and provided a forum for experts to explore the occurrence of gastrointestinal bleeding linked to non-vitamin K antagonist oral anticoagulants in Asian clinical practice for stroke prevention in atrial fibrillation. This report amalgamates insights from two segments of the meeting.

A UK multicentre audit of the management of patients with primary hypercholesterolaemia or mixed dyslipidaemia with bempedoic acid against published lipid-lowering treatment targets

Sudarshan Ramachandran, Amro Maarouf, Karen Mitchell, Tony Avades, Peter Smith, Lee Boulton, Jennifer Kelly, Nitasha Vekaria, Elizabeth Hughes

Article Type

Original Research

Published

08 Aug 2024

This retrospective multicentre audit aimed to evaluate the achievement of lipid-lowering targets with bempedoic acid in UK patients based on recommendations in the Joint British Societies (JBS) guidelines for the prevention of cardiovascular disease.

Sublingually administered bacterial lysates: rationale, mechanisms of action and clinical outcomes

Fulvio Braido, Giovanni Melioli, Gabriele Nicolini, Melissa Ferraris, Stefano Di Girolamo, Mario Di Gioacchino, Giorgio Walter Canonica

Article Type

Review

Published

07 Aug 2024

This review discusses available evidence on the mechanisms of action of bacterial lysates, and the clinical effects of their sublingual administration.