Articles

Antibiotic-induced neuropsychiatric toxicity: epidemiology, mechanisms and management strategies – a narrative literature review

Ali A Althubyani, Samantha Canto, Huy Pham, Dana J Holger, Jose Rey

Article Type

Review

Published

This article reviews the epidemiology of antibiotic-induced neuropsychiatric toxicity, explores potential mechanisms of this adverse event, investigates variations in frequency and clinical presentations between different antibiotic classes causing neuropsychiatric toxicity, and discusses management strategies.

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Nivolumab plus ipilimumab with chemotherapy in metastatic NSCLC: minireview and a case study of a patient negative for PD-L1

Alessandro Morabito

Article Type

Case Report

Published

This article is a minireview on the evolutionary course of non-small-cell lung cancer treatment over recent years, and discusses a case involving a patient who tested negative for PD-L1 but experienced a sustained complete response to explore strategies for addressing this specific tumour context.

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A prospective, observational, multicentre study to evaluate the efficacy of brivaracetam as adjuvant therapy for epilepsy: The Bravo study

Fowzia Siddiqui, Bashir A Soomro, Ehsan U Rehman, Ahsan Numan, Safia Bano, Jawwad Us Salam, Hazim Brohi, Muhammad Zaheer, Faizan Hyder Memon, Muhammad Wahab Qureshi, Junaid Ahmed Sheikh, Abdul Latif Sunejo, Amjad Iqbal, Saira Abbass, Saba Zaidi, Sidrah Nawaz, Kaukab Fatima, Samar Altaf, Neeta Maheshwary, Muhammad Athar Khan, Arjumand Ahmed, Muhammad Iqbal Asif

Article Type

Original Research

Published

The objective of this study was to assess the effectiveness of Brivera when used as an adjunctive therapy for individuals diagnosed with epilepsy.

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Effect of norethisterone dose and duration in the management of abnormal uterine bleeding: a narrative review and case report

Arun Madhab Boruah, Dibyendu Banerjee, Farendra Bhardwaj, Subash Mallya, Rajat Singal, Sugandha Sharma, Ashutosh Gautam

Article Type

Review

Published

The present review summarizes the epidemiology and diagnosis of abnormal uterine bleeding, with a focus on the safety, efficacy and tolerability of norethisterone/norethisterone acetate in abnormal uterine bleeding management, as well as a case of abnormal uterine bleeding in a 40-year-old woman, who was treated with NETA tablets.

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