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Geriatrics

TAS-102 in metastatic colorectal cancer (mCRC): efficacy, tolerability, and quality of life in heavily pretreated elderly patients: a real-life study

Authors: Giuseppe Cicero MD PhD, Raffaele Addeo MD, Rossella De Luca PhD, Giuseppe Lo Re MD PhD, Leonardo Gulotta MD, Pierenrico Marchesa MD, Gaspare Gulotta MD PhD

This study evaluates the safety and
efficacy of TAS-102 in heavily pretreated elderly patients with
metastatic colorectal cancer.

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Urinary tract infections in the elderly: a review of disease characteristics and current treatment options

Authors: Leocadio Rodriguez-Mañas MD, PhD

This narrative review considers the characteristics of urinary tract infections – prevalence and incidence, disease burden, risk factors, and clinical presentation – in the elderly, and examines current treatment options to manage urinary tract infections in the community.

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Combination therapy in the treatment of hypertension

Authors: Carolina Guerrero-García MD, Alberto Francisco Rubio-Guerra PhD

This article reviews the latest information available regarding the treatment of hypertension with combination therapy.

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Suvorexant for insomnia in older adults: a perspective review

Authors: Rajesh R Tampi, Geetha Manikkara, Silpa Balachandran, Piyush Taparia, Stephanie Hrisko, Shilpa Srinivasan, Deena J Tampi

This review identifies published randomized control trials that evaluate the efficacy and tolerability of suvorexant for the treatment of insomnia among older adults.

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Analgesics in the management of behavioral and psychological symptoms of dementia: a perspective review

Authors: Rajesh R Tampi, Corey Hassell, Pallavi Joshi, Deena J Tampi

This review assesses the efficacy and tolerability of analgesics in reducing behavioral and psychological symptoms of dementia among older adults from published randomized controlled trials.

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