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Respiratory

Paediatrics: how to manage acute asthma exacerbations

Authors: James S Leung

This article is an evidence-based review of the medications used to manage paediatric acute asthma exacerbations.

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Paediatrics: how to manage obstructive sleep apnoea syndrome

Authors: Theresa NH Leung, James WCH Cheng, Anthony KC Chan

This article provides a narrative review on the current diagnostic and treatment options for paediatric OSAS.

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Current therapeutic strategies in connective tissue disease-related interstitial lung disease: introduction to the special issue

Authors: Gian Luca Erre MD, PhD, Arduino Aleksander Mangoni MD

This Editorial introduces the Special Issue on the efficacy and safety of current treatment strategies for patients with connective tissue disease-related interstitial lung disease, including the use of immunosuppressants, such as cyclophosphamide, mycophenolate mofetil and rituximab, and antifibrotic drugs.

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Efficacy of cyclophosphamide in treating connective tissue disease-related interstitial lung diseases

Authors: Valeria Nucera MD, Elisabetta Gerratana MD, Manuela Giallanza MD, Laura La Corte MD, Donatella Sangari MD, Fabiola Atzeni MD, PhD

This review focuses on cyclophosphamide due to its crucial role in the treatment of systemic sclerosis-related interstitial lung disease, particularly in the case of patients with progressive Interstitial lung diseases.

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Efficacy and safety of mycophenolate mofetil in the treatment of rheumatic disease-related interstitial lung disease: a narrative review

Authors: Giulia Cassone MD, PhD, Marco Sebastiani MD, Caterina Vacchi MD, PhD, Gian Luca Erre MD, Carlo Salvarani MD, Andreina Manfredi MD, PhD

This review describes the available data and recent advances on the effectiveness and safety of MMF for the treatment of ILD related to RD, including rheumatoid arthritis, systemic sclerosis, primary Sjögren syndrome, systemic lupus erythematosus, idiopathic inflammatory myopathies, undifferentiated connective tissue disease, interstitial pneumonia with autoimmune features and antineutrophil cytoplasmic antibody-associated vasculitis.

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