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Cardiology and cardiovascular disease

Nail enthesis ultrasound and automated software-guided assessment of bilateral common carotid intima–media thickness in psoriasis and psoriatic arthritis: is there a correlation with clinical and laboratory findings?

Authors: José Alexandre Mendonça PhD, Lucas Nogueira Pansani MD, Mateus Basso Mimoto MD, Igor Tadeu Garcia Ferreira MD, Fernanda Bertucci Sanches MD, Thais de Campos Ferreira Pinto MD, Vania Aparecida Leandro-Merhi PhD, José Luis Braga de Aquino PhD

The objective of this study was to detect and correlate the changes that indicate the inflammatory and atherosclerotic process in psoriasis and psoriatic arthritis patients, using nail ultrasound and carotid artery intima–media thickness radiofrequency software.

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DAPA-HF trial: dapagliflozin evolves from a glucose-lowering agent to a therapy for heart failure

Authors: Edgardo Kaplinsky MD

This review describes the results of the DAPA-HF (Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure) trial and the recently published Dapagliflozin Effects on Biomarkers, Symptoms, and Functional Status in Patients With Heart Failure With Reduced Ejection Fraction (DEFINE-HF) trial. In addition, the thought-to-be mechanisms of action of SGLT2 inhibitors beyond their known glucose-lowering effects.

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Expanding horizons for clinical applications of chloroquine, hydroxychloroquine, and related structural analogues

Authors: Ashutosh M Shukla MD, Aparna Wagle Shukla MD

This article reviews the expanding clinical applicability of chloroquine and related drugs includes rheumatological and cardiovascular disorders (CVD), chronic kidney disease (CKD), oncology, and a variety of nonmalarial infections.

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Clinical profile and management of rivaroxaban in patients with atrial fibrillation in routine practice in Spain: data from six nationwide studies

Authors: Manuel Anguita MD, Mariano de la Figuera MD, Alejandro I Pérez Cabeza MD, Carmen Suarez Fernández MD

This work analyzed the clinical profile and management of patients with nonvalvular atrial fibrillation taking rivaroxaban in routine practice in Spain.

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Therapeutic management of hyperlipoproteinemia (a)

Authors: Constantine E Kosmas MD, PhD, Andreas Sourlas, Gordon Mallarkey PhD, Delia Silverio MD, Domingo Y Ynoa MD, Peter D Montan MD, Eliscer Guzman MD, Mario J Garcia MD

This review presents and discusses the current clinical and scientific data pertaining to the therapeutic options for the management of hyperlipoproteinemia (a).

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