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Cardiology and cardiovascular disease

Primary genetic disorders affecting high density lipoprotein (HDL)

Authors: Constantine E Kosmas MD, PhD, Delia Silverio MD, Andreas Sourlas, Frank Garcia MD, Peter D Montan MD, Eliscer Guzman MD

This review aims to describe certain genetic disorders associated with either low or high plasma HDL-C and discuss their clinical features, associated risk for cardiovascular events, and treatment options.

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Spectral Doppler and automated software-guided ultrasound assessment of bilateral common carotid intima-media thickness in spondyloarthritis: is there a correlation with clinical findings?

Authors: José Alexandre Mendonça PhD, Beatriz Bisetto de Andrade MD, José Luis Braga de Aquino PhD, Vania Aparecida Leandro-Merhi PhD, Guilherme B Damian MD

This study evaluates the correlation between articular and carotid ultrasound data and laboratory and clinical variables in patients with spondyloarthritis.

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Sacubitril/valsartan: evaluation of safety and efficacy as an antihypertensive treatment

Authors: Sarah L Anderson PharmD, Joel C Marrs PharmD

This review examines sacubitril/valsartan, which has demonstrated safety and efficacy when it comes to blood pressure lowering, making it a promising antihypertensive agent.

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Adding ezetimibe to statin therapy: latest evidence and clinical implications

Authors: Marija Vavlukis MD, PhD, FESC, Ana Vavlukis MSc

This review examines the therapeutic efficacy and safety of ezetimibe in combination therapy with statins and its potential side effects.

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Combination therapy in the treatment of hypertension

Authors: Carolina Guerrero-García MD, Alberto Francisco Rubio-Guerra PhD

This article reviews the latest information available regarding the treatment of hypertension with combination therapy.

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