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Haematology and Oncology

Management of adverse effects of new monoclonal antibody treatments in acute lymphoblastic leukemia

Authors: Diego Conde-Royo MD, Luis Miguel Juárez-Salcedo MD, Samir Dalia MD

This article reviews the unique toxicities and adverse effects of blinatumomab and inotuzumab ozogamicin and provide recommendations for prevention of adverse effects as well as the management options for each medication.

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TAS-102 in metastatic colorectal cancer (mCRC): efficacy, tolerability, and quality of life in heavily pretreated elderly patients: a real-life study

Authors: Giuseppe Cicero MD PhD, Raffaele Addeo MD, Rossella De Luca PhD, Giuseppe Lo Re MD PhD, Leonardo Gulotta MD, Pierenrico Marchesa MD, Gaspare Gulotta MD PhD

This study evaluates the safety and
efficacy of TAS-102 in heavily pretreated elderly patients with
metastatic colorectal cancer.

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Cutaneous adverse events and quality of life in outpatients receiving anticancer agents: results from an observational, cross-sectional study

Authors: Hae-Jin Suh Oh MD, Ángeles Flórez Menéndez PhD, Víctor Sacristán Santos MD, Francisca Fernández Ribeiro PharmD, Lucía Vilanova-Trillo DNP, Manuel Constenla Figueiras PhD, Manuel Pereiro Ferreiros PhD

This study evaluates the impact of cutaneous adverse events on quality of life in outpatients receiving anticancer drugs and aims to determine the differences in quality of life between conventional chemotherapy versus targeted therapies.

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Mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL) epidemiology and treatment pathway in Spain: new insights for an accurate description

Authors: Paolo D’Agostino MSc, Alan Kent BSc (Hons), Eric Sharp MRSB, Fabian Schmidt Dipl.Kfm, Marco Turini MSc

This study aims to (1) provide an estimate for the prevalence of treated mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL) patients in Spain, (2) describe the Spanish patient treatment pathways for MF-CTCL, including quantification of the distribution of patients between primary, secondary and tertiary care institutions, and (3) investigate and quantify the treatment preferences of physicians.

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Topical treatment of radiation-induced dermatitis: current issues and potential solutions

Authors: Nicola Alessandro Iacovelli MD, Yvan Torrente MD, PhD, Adriana Ciuffreda MD, Vittorio A Guardamagna MD, PhD, Marta Gentili MS, Luca Giacomelli PhD, Paola Sacerdote PhD

The aim of this paper is to discuss current knowledge on radiation-induced dermatitis and propose targets for the prevention/treatment of this
condition. On these bases, the characteristics of the ‘ideal’
compound to address this side effect will be described.

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