Antibiotic-induced neuropsychiatric toxicity: epidemiology, mechanisms and management strategies – a narrative literature review

Ali A Althubyani, Samantha Canto, Huy Pham, Dana J Holger, Jose Rey

Article Type

Review

Published

This article reviews the epidemiology of antibiotic-induced neuropsychiatric toxicity, explores potential mechanisms of this adverse event, investigates variations in frequency and clinical presentations between different antibiotic classes causing neuropsychiatric toxicity, and discusses management strategies.

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High-dose amphotericin: yay or nay? A case series and literature review

Kayla R Stover, Taylor E Jordan, Jamie L Wagner, Katie E Barber

Article Type

Review

Published

This case series and literature review characterizes high-dose lipid formulation amphotericin B use and describes the therapeutic effects of high-dose lipid formulations of amphotericin B on patients at one institution and in the literature.

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Antifungal resistance, combinations and pipeline: oh my!

Kayla R Stover, Brandon K Hawkins, J Myles Keck, Katie E Barber, David A Cretella

Article Type

Review

Published

The purpose of this review is to discuss resistance mechanisms and challenges with currently available agents, provide evidence for combination therapy, and evaluate the newly available and upcoming antifungal agents and their proposed place in the treatment of challenging fungal infections.

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