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Infectious disease

Thalidomide and discoid lupus erythematosus: case series and review of literature

Authors: Giovanna Malara, Chiara Verduci, Maria Altomonte, Maria Cuzzola, Caterina Trifirò, Cristina Politi, Giovanni Tripepi

This article reports four cases of discoid lupus erythematosus treated previously with the most common immunomodulatory agents with no results and finally successfully treated with thalidomide.


Paediatrics: how to manage pediculosis capitis

Authors: Alexander KC Leung, Joseph M Lam, Kin Fon Leong, Benjamin Barankin, Kam Lun Hon

Pediculosis capitis is a common human parasitic infestation in childhood. This article aims to provide a narrative updated review on the management of pediculosis capitis.


Open-label use of an aliphatic polyamine immunomodulator in patients hospitalized with COVID-19

Authors: Sergey V Efimov, Natallia V Matsiyeuskaya, Olga V Boytsova, Luydmila Yu Akhieva, Elena V Kuntsevich, Anastasia A Troshina, Elena I Kvasova, Anton A Tikhonov, Nadezhda F Khomyakova, Francisco Harrison, Jean-François Rossi, Timothy C Hardman

This study evaluated the safety and efficacy of azoximer bromide when used in combination with standard of care treatment in patients hospitalized with COVID-19.


HIV: how to manage low-level viraemia in people living with HIV

Authors: Emily K Hanners, Jessica Benitez-Burke, Melissa E Badowski

This is a narrative review of the growing evidence of low-level viraemia in people living with HIV to determine risk factors and antiretroviral therapy management strategies and to discuss the implications of low-level viraemia on the development of future virological failure.


HIV: how to manage heavily treatment-experienced patients

Authors: Stephanie Spivack, Stephen Pagkalinawan, Rafik Samuel, David E Koren

This narrative review provides an overview of the clinician approach to care, including diagnostics, approaches to regimen creation, relevant resources, and a broad array of
both currently available and upcoming antiretrovirals that may be used in regimens for heavily treatment-experienced patients.