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Infectious disease

Challenges and research priorities to progress the impact of antimicrobial stewardship

Authors: Matteo Bassetti MD, PhD, Daniele Roberto Giacobbe MD, Antonio Vena MD, PhD, Adrian Brink MMed

This review discusses and explains the most important challenges faced by antibiotic stewardship and antifungal stewardship programmes and suggests areas for further research.

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Oral oncolytic and antiretroviral therapy administration: dose adjustments, drug interactions, and other considerations for clinical use

Authors: Melissa E Badowski PharmD, MPH, Bradley Burton PharmD, Kristy M Shaeer PharmD, MPH, John Dicristofano BS, PharmD Candidate

This article evaluates existing literature through such means as drug databases and package inserts along with PubMed/Medline, Embase, and Google Scholar databases to develop a reference tool for providers to utilize when there is a decision to treat a patient with ART and oral oncolytic agents concurrently.

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Penile warts: an update on their evaluation and management

Authors: Alexander KC Leung MBBS, FRCPC, FRCP (UK and Irel), FRCPCH, FAAP, Benjamin Barankin MD, FRCPC, Kin Fon Leong MBBS, MRCPCH, Kam Lun Hon MD, FAAP, FCCM

This articles provides an update on the current understanding, evaluation, and management of penile warts.

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Treatment of acute bacterial skin and skin structure infection with single-dose dalbavancin in persons who inject drugs

Authors: Pedro Luis Gonzalez MD, MT, Urania Rappo MD, Karthik Akinapelli MS, Jennifer S McGregor RPh, Sailaja Puttagunta MD, Michael W Dunne MD

This subgroup analysis sought to more fully characterize the demographics, baseline characteristics, safety, and efficacy of
dalbavancin in the persons who inject drugs (PWID) and non-PWID population and as a single-dose therapy versus 2-dose therapy from a previously published global trial.

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How to manage Pseudomonas aeruginosa infections

Authors: Matteo Bassetti MD, PhD, Antonio Vena MD, Antony Croxatto PhD, Elda Righi MD, PhD, Benoit Guery MD, PhD

This review looks at the mechanisms associated with resistance to Pseudomonas aeruginosa, as well as antibiotic combinations and limitations of current therapies, and the potential for alternative drugs and new therapeutic options are also discussed.

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