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Infectious disease

Paediatrics: how to manage scabies

Authors: Russell Thompson, Sean Westbury, Dana Slape

This narrative review addresses scabies, a highly contagious, pruritic infestation of the skin caused by the mite Sarcoptes scabiei var hominis. It also provides a summary of treatments and recommendations for the management of paediatric scabies.

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Paediatrics: how to manage viral gastroenteritis

Authors: Alexander KC Leung, Kam Lun Hon

This article aims to provide a narrative updated review on the evaluation and management of viral gastroenteritis in children.

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The effect of azoximer bromide (Polyoxidonium®) in patients hospitalized with coronavirus disease (COVID-19): an open-label, multicentre, interventional clinical study

Authors: Sergey V Efimov, Natallia V Matsiyeuskaya, Olga V Boytsova, Lyudmila Yu Akhieva, Elena I Kvasova, Francisco Harrison, Yulia S Karpova, Anton Tikhonov, Nadezhda F Khomyakova, Tim Hardman, Jean-François Rossi

The aim of this study was to observe the safety and efficacy of AZB as an addition to the complex treatment of patients hospitalized with COVID-19. This study is the first exploratory
use of AZB in patients with COVID-19.

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The race to a COVID-19 vaccine: opportunities and challenges in development and distribution

Authors: Rodrigo M Burgos, Melissa E Badowski, Emily Drwiega, Samaneh Ghassemi, Nikki Griffith, Fischer Herald, Mikayla Johnson, Renata O Smith, Sarah M Michienzi

This article discusses the unprecedented toll of COVID-19 and how it jumpstarted the race towards potential COVID-19 vaccinations, which have been developed in less than a year. It discusses how this feat was accomplished, and how clinical development, manufacturing scale-up and distribution are occurring in parallel for the four COVID-19 vaccine front-runners. It also discusses the many challenges that still lie ahead.

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Current treatment in COVID-19 disease: a rapid review

Authors: Miguel Rodriguez-Guerra, Preeti Jadhav, Timothy J Vittorio

This review aims to assess the efficacy and safety of available therapies for COVID-19 in light of current evidence. These treatment options are compared based on their impact on symptom management, inpatient length of stay, and overall morbidity and mortality.

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