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Cardiology and cardiovascular disease

Sacubitril/valsartan: evaluation of safety and efficacy as an antihypertensive treatment

Authors: Sarah L Anderson PharmD, Joel C Marrs PharmD

This review examines sacubitril/valsartan, which has demonstrated safety and efficacy when it comes to blood pressure lowering, making it a promising antihypertensive agent.


Adding ezetimibe to statin therapy: latest evidence and clinical implications

Authors: Marija Vavlukis MD, PhD, FESC, Ana Vavlukis MSc

This review examines the therapeutic efficacy and safety of ezetimibe in combination therapy with statins and its potential side effects.


Combination therapy in the treatment of hypertension

Authors: Carolina Guerrero-García MD, Alberto Francisco Rubio-Guerra PhD

This article reviews the latest information available regarding the treatment of hypertension with combination therapy.


Cardiac myosin activators for heart failure therapy: focus on omecamtiv mecarbil

Authors: Edgardo Kaplinsky MD, Gordon Mallarkey PhD

This article examines omecamtiv mecarbil, which is a first-in-class cardiac myosin activator used in the treatment of heart failure.


High-density lipoprotein (HDL) functionality and its relevance to atherosclerotic cardiovascular disease

Authors: Constantine E Kosmas MD, PhD, Ian Martinez MD, Andreas Sourlas, Kyriaki V Bouza MD, Frederick N Campos MD, Verenisse Torres MD, Peter D Montan MD, Eliscer Guzman MD

This review aims to present and discuss the current clinical and scientific evidence pertaining to the significance of HDL functionality over the actual HDL-C concentration in mediating the favorable effects on the cardiovascular system.