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Tag "Type 2 diabetes"

Clinical potential of treatment with semaglutide in type 2 diabetes patients

Authors: Michael E Røder

This review discusses the efficacy and safety of semaglutide, which have
been investigated in an extensive clinical development
program including more than 9,000 patients with type 2
diabetes.

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Metformin in the management of diabetes during pregnancy and lactation

Authors: Gagan Priya MD, DM, Sanjay Kalra MD, DM

This review explores the current place of metformin in the management of gestational diabetes and type 2 diabetes during pregnancy and lactation.

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Resource use and outcomes associated with initiation of injectable therapies for patients with type 2 diabetes mellitus

Authors: Richard Brice, Sharon Shelley, Pankaj Chaturvedi, Divina Glah, Donna Ashley, Monica Hadi

Management of type 2 diabetes mellitus (T2DM) often requires intervention with oral and injectable therapies. Across National Health Service (NHS) England, injectable therapies may be initiated in secondary, intermediate or primary care. This original research set out to understand resource utilization, the pathways of care, clinical outcomes, and experience of patients with T2DM
initiated on injectable therapies.

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Empagliflozin: a new sodium-glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes

Authors: Joshua J Neumiller

Type 2 diabetes is increasing in prevalence worldwide, and hyperglycemia is often poorly controlled despite a number of therapeutic options.

Unlike previously available agents, sodium-glucose co-transporter 2 inhibitors offer an insulin-independent mechanism for improving blood glucose levels, since they promote urinary glucose excretion by inhibiting glucose reabsorption in the kidney.

In this article, the author discusses empagliflozin and based on available data, it appears that this drug may be a useful option in a range of patients; however, clinical decisions will be better informed by the results of ongoing studies, in particular, a large cardiovascular outcome study (EMPA-REG OUTCOME™).

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