Review
The aim of this narrative review is to explore the relationship between high-rate breakthrough cancer pain, which strongly impacts health-related quality of life and tumour characteristics, in the face of novel approaches that should provide guidance for future clinical practice.
Review
This is a critical narrative review focusing on HR+/human epidermal growth factor receptor 2-negative (HER2–) de novo metastatic breast cancer in terms of genomic, biological, pathological, and clinical features and outcomes after systemic and locoregional treatments, outlining differences with recurrent metastatic breast cancer.
Review
This article offers a review of the more recently published results on the Janus kinase inhibitor inhibitor upadacitinib and its use in the treatment of psoriatic arthritis.
Original Research
Prucalopride is a selective serotonin type 4 (5-HT4) receptor agonist indicated for treatment of chronic idiopathic constipation in adults. 5-HT4 receptors are present in the central nervous system; therefore, this article discusses non-clinical and clinical assessments evaluating the tissue distribution and abuse potential of prucalopride.
Review
This manuscript offers detailed guidance on how to design and implement an outpatient antimicrobial stewardship programme and reviews the literature on current strategies. Challenges related to initiating and maintaining outpatient stewardship efforts are also discussed
