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Respiratory

Agents to treat BRAF-mutant lung cancer

Authors: Jean G Bustamante Alvarez MD, MS, Gregory A Otterson MD

Keywords: dabrafenib, immunotherapy, lung neoplasm, protooncogene protein B-raf, trametinib. Citation: Bustamante Alvarez JG, Otterson GA. Agents to treat BRAF-mutant lung cancer. Drugs in Context 2019; 8: 212566. DOI: 10.7573/dic.212566 Contributions: Both authors contributed equally to the preparation of this review.

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Severe refractory asthma: current treatment options and ongoing research

Authors: Francesco Menzella MD, Francesca Bertolini MSc, PhD, Mirella Biava MSc, Carla Galeone MSc, Chiara Scelfo MD, Marco Caminati MD

In this review, the different biological options available for the treatment of severe refractory asthma, their mechanism of action, and the overlapping aspects of their usage in clinical practice are discussed.

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Sublingual allergen immunotherapy for respiratory allergy: a systematic review

Authors: Carlos Blanco MD, PhD, Raphaelle Bazire MD, Laura Argiz MD, Jenaro Hernández-Peña MD, PhD

This systematic review provides complete and updated information on efficacy and safety of sublingual immunotherapy (SLIT) formulations for the treatment of allergic respiratory diseases (ARDs).

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Satisfaction and quality of life of allergic patients following sublingual five-grass pollen tablet immunotherapy in Spain

Authors: Darío Antolín-Amerigo, Isabel A Tabar, Maria del Mar Fernández-Nieto, Anna M Callejo-Melgosa, Francisco J Muñoz-Bellido, José C Martínez-Alonso, Jorge D Méndez-Alcalde, Marta Reche, Ana Rodríguez-Trabado, Ana Rosado-Ingelmo, Alicia Alonso-Gómez, Rosa Blanco-González, José A Alvarez-Fernandez, Isabel Botella, Ana Valls, Mercedes Cimarra, Carlos Blanco

This trial sought to determine the satisfaction and health-related quality of life (HRQoL) of patients undergoing five-grass pollen tablet treatment.

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Bilastine in allergic rhinoconjunctivitis and urticaria: a practical approach to treatment decisions based on queries received by the medical information department

Authors: Amalia Leceta, Ander Sologuren, Román Valiente, Cristina Campo, Luis Labeaga

Overall, this analysis highlights gaps in our knowledge regarding the optimal use of bilastine. Expert opinion based upon an understanding of the science can help in the decision-making, but more research is needed to provide evidence-based answers in certain circumstances.

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