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Respiratory

Probabilistic data linkage: a case study of comparative effectiveness in COPD

Authors: Christopher M Blanchette, Mitch DeKoven, Ajita P De, Melissa Roberts

In this era of comparative effectiveness research, new, advanced techniques are being investigated by the research community to overcome the limitations of existing data sources. In this article Dr Christopher Blanchette and his co-authors describe the approach of probabilistic data linkage as a means to address this critical issue.

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Is ‘GOLD’ standard for the management of COPD in clinical practice?

Authors: Barbara P Yawn

Primary therapy for chronic obstructive pulmonary disease (COPD) is the removal of the toxic agent (in most cases, tobacco smoke). Additional therapy includes bronchodilators. Inhaled corticosteroids and long-acting bronchodilators can be used to prevent and reduce the risk of exacerbations. COPD is a systemic disease and often requires therapy of its protean-associated morbidities from depression to osteoporosis and muscle wasting. Despite pessimism from some, COPD is treatable.

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