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Neurology

Efficacy and safety of a GABAergic drug (Gamalate® B6): effects on behavior and cognition in young adults with borderline-to-mild intellectual developmental disabilities and ADHD

Authors: Ramón Novell MD, Susanna Esteba-Castillo PhD, Emili Rodriguez PhD

Gamalate B6 was evaluated in patients
with borderline intellectual functioning or mild intellectual
development disability and found to be effective and well tolerated for ADHD and challenging behavior.

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Anti-NMDA receptor encephalitis: a case study and illness overview

Authors: Brian Ford MD, Alex McDonald MD, Shilpa Srinivasan MD, DFAPA

This review on anti-N-methyl D-aspartate (NMDA) receptor (anti-NMDAR) encephalitis provides a case presentation and the timeline of symptoms seen over the course of the illness. Key findings in the literature about anti-NMDAR encephalitis are highlighted to facilitate diagnostic consideration and treatment.

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From medications to surgery: advances in the treatment of motor complications in Parkinson’s disease

Authors: Kanae Jennifer Nagao MBBS (Hons), FRACP, Neepa J Patel MD

This review provides an overview of the pharmacologic and surgical therapies currently available and under investigation for the treatment of motor fluctuations and dyskinesia in Parkinson’s disease.

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Mitochondrial disorders and drugs: what every physician should know

Authors: Daniele Orsucci MD, Elena Caldarazzo Ienco MD, Gabriele Siciliano MD, PhD, Michelangelo Mancuso MD, PhD

Keywords: coenzyme Q10, drugs, mitochondria, mtDNA, mitochondrial diseases, toxicity Citation: Orsucci D, Caldarazzo Ienco E, Siciliano G, Mancuso M. Mitochondrial disorders and drugs: what every physician should know. Drugs in Context 2019; 8: 212588. DOI: 10.7573/dic.212588 Contributions: All authors contributed

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Use of botulinum toxin for movement disorders

Authors: Carlos Henrique Ferreira Camargo MD, MSc, PhD, Hélio Afonso Ghizoni Teive MD, MSc, PhD

The aim of this review is to present the new and well-established uses of botulinum toxin for movement disorders.

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