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Immunology

The biosimilars journey: current status and ongoing challenges

Authors: Igor Age Kos MD, Valderílio Feijó Azevedo MD, PhD, Daniel Egg Neto, Sérgio Cândido Kowalski MD, PhD

Biosimilar products are already approved and marketed in several countries. This review focuses on remaining challenges regarding biosimilars, such as the lack of regulatory harmony, especially concerning naming, the marketed intended copies, the interchangeability, and the biosimilars in orphan diseases.

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Spectral Doppler and automated software-guided ultrasound assessment of bilateral common carotid intima-media thickness in spondyloarthritis: is there a correlation with clinical findings?

Authors: José Alexandre Mendonça PhD, Beatriz Bisetto de Andrade MD, José Luis Braga de Aquino PhD, Vania Aparecida Leandro-Merhi PhD, Guilherme B Damian MD

This study evaluates the correlation between articular and carotid ultrasound data and laboratory and clinical variables in patients with spondyloarthritis.

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The latest evidence for possible HIV-1 curative strategies

Authors: Hanh Thi Pham PhD, Thibault Mesplède PhD

This review focuses on some of the current curative strategies aiming at providing a sterilizing or functional cure to HIV-1-positive individuals.

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Satisfaction and quality of life of allergic patients following sublingual five-grass pollen tablet immunotherapy in Spain

Authors: Darío Antolín-Amerigo, Isabel A Tabar, Maria del Mar Fernández-Nieto, Anna M Callejo-Melgosa, Francisco J Muñoz-Bellido, José C Martínez-Alonso, Jorge D Méndez-Alcalde, Marta Reche, Ana Rodríguez-Trabado, Ana Rosado-Ingelmo, Alicia Alonso-Gómez, Rosa Blanco-González, José A Alvarez-Fernandez, Isabel Botella, Ana Valls, Mercedes Cimarra, Carlos Blanco

This trial sought to determine the satisfaction and health-related quality of life (HRQoL) of patients undergoing five-grass pollen tablet treatment.

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Influenza vaccination: key facts for general practitioners in Europe—a synthesis by European experts based on national guidelines and best practices in the United Kingdom and the Netherlands

Authors: George Kassianos, Patricia Blank, Oana Falup-Pecurariu, Ernest Kuchar, Jan Kyncl, Raul Ortiz De Lejarazu, Aneta Nitsch-Osuch, Gerrit A Van Essen

In this article the authors aim to harmonise the diagnosis of seasonal influenza and the approach of European general practitioners to vaccination in order to better identify influenza outbreaks and achieve a target vaccination rate of 75% throughout Europe.

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