The convergent pathway of obstructive lung disease: the disease-modifying potential of dipeptidyl peptidase 1 inhibition in COPD, asthma and bronchiectasis overlap

Francesco Menzella, Marcello Cottini, Carlo Lombardi, Rory Chan

Article Type

Review

Published

This review synthesizes the pathophysiology and key aspects of bronchiectasis–COPD overlap syndrome and analyses the clinical evidence for brensocatib as the first potential disease-modifying therapy for this neutrophilic endotype designed to break the cycle.

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Holistic care in mild upper respiratory tract infections (MURTIs): an approach to individualized care management

Andrew Smith, Guillermo Estrada Riolobos, Marco Biagi, Andreas Michalsen, Laura Sadofsky, Ann Herzeel, Patrick Poucheret

Article Type

Review

Published

This article presents a patient-centred classification system for mild upper respiratory tract infections and proposes a 360° holistic care model that tailors effective, safe and suitable treatment to each individual’s symptoms and circumstances.

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Tezepelumab for early-onset severe allergic asthma with persistent airflow limitation and small airway dysfunction: a treatable traits approach

Francesco Menzella, Claudio Sorino, Carlo Lombardi, Annamaria Bosi, Silvia Tonin, Lorenzo Corsi, Andrea Ballarin, Marcello Cottini

Article Type

Case Report & Review

Published

This article describes the clinical and functional evolution of a young patient with severe early-onset allergic asthma with impaired respiratory function treated with the anti-thymic stromal lymphopoietin biologic agent tezepelumab.

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Nurses’ perceptions on the usability of the Hyrimoz® Sensoready® autoinjector device

Charlotte Both, Elena Bachinskaya, Laura Rose, Carol M Antequera, Jessica R Allegretti

Article Type

Original Research

Published

This survey of gastroenterology nurses in the USA was designed to assess nurses’ perceptions regarding the Hyrimoz Sensoready pen, and the degree to which unique features might influence patient education when compared with the reference medicine autoinjector device, the Humira pen.

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