Switching from multiple-inhaler triple therapy to single, extra fine-inhaler triple therapy in severe refractory asthma with EGPA: beyond control. Case report and review of the literature

Francesco Menzella, Marcello Cottini, Silvia Tonin, Lorenzo Corsi, Annamaria Bosi, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Matteo Tacconi, Carlo Lombardi

Article Type

Case Report & Review

Published

This case report describes a 69-year-old male with severe, poorly controlled asthma who was diagnosed with eosinophilic granulomatosis with polyangiitis, it also presents a review of the literature on eosinophilic granulomatosis with polyangiitis and asthma management.

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Clinical remission and control in severe asthma: agreements and disagreements

Annamaria Bosi, Carlo Lombardi, Cristiano Caruso, Marcello Cottini, Ilaria Baglivo, Stefania Colantuono, Francesco Menzella

Article Type

Review

Published

This narrative review aims to frame the evolution of the debated concept of clinical remission as an ambitious and now concretely achievable outcome in modern asthma management, to highlight correct management of inhaled therapies, oral corticosteroids and biological drugs in this context, and, finally, to provide clinicians with insights that could be useful to achieve remission in the greatest possible number of patients.

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Rapid response on facial psoriasis to bimekizumab: case series

Nicoletta Bernardini, Annunziata Dattola, Giacomo Caldarola, Diego Orsini, Chiara Assorgi, Alessandra D’Amore, Giulia Maretti, Antonio Giovanni Richetta, Ersilia Tolino, Nevena Skroza, Concetta Potenza

Article Type

Case Series

Published

This case series represents the first clinical real-life experience of rapid and successful management of facial psoriasis with bimekizumab in six patients.

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Severe hypereosinophilia in a patient treated with dupilumab and shift to mepolizumab: the importance of multidisciplinary management. A case report and literature review

Sara Munari, Giulia Ciotti, Walter Cestaro, Lorenzo Corsi, Silvia Tonin, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Annamaria Bosi, Matteo Tacconi, Francesco Gialdini, Michele Gottardi, Francesco Menzella

Article Type

Review

Published

This article describes a case of severe hypereosinophilia in a patient with chronic rhinosinusitis with nasal polyps and asthma treated with dupilumab and a subsequent therapeutic shift to mepolizumab that led to maintenance of symptom control and concomitant normalization of blood eosinophil count.

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