Dupilumab reduces patient-reported cough and improves quality of life in patients with severe eosinophilic asthma with or without chronic rhinosinusitis with nasal polyps: a real-life prospective study

Carlo Lombardi, Alvise Berti, Francesco Menzella, Marcello Cottini

Article Type

Original Research

Published

The objective of this study was to assess the impact of dupilumab on chronic cough in patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps.

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Switching from multiple-inhaler triple therapy to single, extra fine-inhaler triple therapy in severe refractory asthma with EGPA: beyond control. Case report and review of the literature

Francesco Menzella, Marcello Cottini, Silvia Tonin, Lorenzo Corsi, Annamaria Bosi, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Matteo Tacconi, Carlo Lombardi

Article Type

Case Report & Review

Published

This case report describes a 69-year-old male with severe, poorly controlled asthma who was diagnosed with eosinophilic granulomatosis with polyangiitis, it also presents a review of the literature on eosinophilic granulomatosis with polyangiitis and asthma management.

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Clinical remission and control in severe asthma: agreements and disagreements

Annamaria Bosi, Carlo Lombardi, Cristiano Caruso, Marcello Cottini, Ilaria Baglivo, Stefania Colantuono, Francesco Menzella

Article Type

Review

Published

This narrative review aims to frame the evolution of the debated concept of clinical remission as an ambitious and now concretely achievable outcome in modern asthma management, to highlight correct management of inhaled therapies, oral corticosteroids and biological drugs in this context, and, finally, to provide clinicians with insights that could be useful to achieve remission in the greatest possible number of patients.

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