Haematology and Oncology Archives - Page 2 of 21

Long sustained response during second-line pembrolizumab plus lenvatinib in a patient with recurrent endometrial carcinoma: a case report

Laura Fabbri, Linda Galvani, Claudio Zamagni

Article Type

Case Report

Published

24 Jun 2025

A clinical case report with a favourable outcome aiming to compare the patient’s response and tolerability with efficacy and toxicity data reported in clinical studies.

Sustained disease control with pembrolizumab-lenvatinib in a patient with heavily pre-treated recurrent endometrial carcinoma: a case report

Alessia Lancianese, Elena Maccaroni, Laura Zepponi, Riccardo Giampieri, Rossana Berardi

Article Type

Case Report

Published

24 Jun 2025

This article presents a case of advanced mismatch repair proficiency/microsatellite stable endometrial carcinoma that was successfully treated with pembrolizumab plus lenvatinib
after chemotherapy failure.

Platinum-induced ototoxicity and hearing impairment in children and adolescents

Alberto Romano, Giorgio Attinà, Palma Maurizi, Dario Talloa, Stefano Mastrangelo, Antonio Ruggiero

Article Type

Case Report

Published

05 Jun 2025

This narrative review aims to present the latest data on ototoxicity induced by platinum-based chemotherapy.

Patterns of treatment and outcomes of patients with metastatic HER2-low breast cancer treated with CDK4/6 inhibitors and hormone therapy

Federico Sottotetti, Barbara Tagliaferri, Gianpiero Rizzo, Raffaella Palumbo, Giulia Chessa, Chiara Raso, Lorenzo Perrone, Alberto Malovini, Valentina Tibollo, Laura Deborah Locati, Paolo Pedrazzoli, Angioletta Lasagna

Article Type

Original Research

Published

07 May 2025

This study aims to investigate, through a retrospective approach and in a real-world setting, the activity and effectiveness of CDK4/6i as first-line or second-line treatment in a HR+/HER2-low population compared to matched patients with HR+/HER2-0 disease.

Real-life effectiveness of FLOT in resectable gastric cancer: existing challenges

Francesco Serra, Federica Valerio, Paolo Pedrazzoli, Jacopo Viganò, Riccardo Caccialanza, Daniela Cicognini, Anna Pagani, Salvatore Corallo

Article Type

Original Research

Published

18 Feb 2025

This article aims to demonstrate the real-life effectiveness of the fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT) regimen by comparing it with traditional chemotherapy regimens and aims to discover its strengths and weaknesses.