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Haematology and Oncology

Topical treatment of radiation-induced dermatitis: current issues and potential solutions

Authors: Nicola Alessandro Iacovelli MD, Yvan Torrente MD, PhD, Adriana Ciuffreda MD, Vittorio A Guardamagna MD, PhD, Marta Gentili MS, Luca Giacomelli PhD, Paola Sacerdote PhD

The aim of this paper is to discuss current knowledge on radiation-induced dermatitis and propose targets for the prevention/treatment of this
condition. On these bases, the characteristics of the ‘ideal’
compound to address this side effect will be described.

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Temozolomide and oral etoposide in children with recurrent malignant brain tumors

Authors: Antonio Ruggiero MD, Anna Ariano MD, Silvia Triarico MD, Michele Antonio Capozza MD, Alberto Romano MD, Palma Maurizi MD, Stefano Mastrangelo MD, Giorgio Attinà MD

The article reviews the results
derived from the combination use of TMZ and oral VP-16 to treat malignant brain tumors

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Rectal neuroendocrine carcinoma: case report of a rare entity and perspective review of promising agents

Authors: Gabriela Antelo MD, Cinta Hierro MD, MSc, Juan Pablo Fernández MD, Eduardo Baena MD, Cristina Bugés MD, Laura Layos MD, José Luis Manzano MD, Mónica Caro MD, Ricard Mesia MD, PhD

This article discusses the current management of this rare entity and provide an overview of the most relevant molecular findings, whilst illustrating the potential value that prescreening panels can offer, searching for actionable targets (MSI/dMMR, PD-L1, BRAFv600E) to guide therapy with promising agents that could fill a void in this disease.

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Facing the COVID-19 outbreak in children with cancer

Authors: Antonio Ruggiero MD, Alberto Romano MD, Giorgio Attinà MD

This editorial discusses the current COVID-19 outbreak and underlines that hygienic educational programs are fundamental and must be continued and implemented especially for immunosuppressed children.

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Use of anti-CD20 therapy in follicular and marginal zone lymphoma: a review of the literature

Authors: Luis Miguel Juárez-Salcedo MD, Diego Conde-Royo MD, Keina Quiroz-Cervantes MD, Samir Dalia MD

This article discusses the role of mAbs in follicular lymphoma and marginal zone lymphoma along with reviewing the current data about the use of biosimilar mAbs in these diseases.

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