Drugs in Context Haematology welcomes a broad range of article types including original research, study protocols and review articles.
In line with the principle of providing context for healthcare professionals (HCPs) to properly inform and improve disease management in real world medicine, we especially encourage the submission of articles that provide context for trials of drug interventions in order to motivate improvements in disease management by HCPs practising medicine in the front line.
Review
The aim of this narrative review is to explore the relationship between high-rate breakthrough cancer pain, which strongly impacts health-related quality of life and tumour characteristics, in the face of novel approaches that should provide guidance for future clinical practice.
Review
This is a critical narrative review focusing on HR+/human epidermal growth factor receptor 2-negative (HER2–) de novo metastatic breast cancer in terms of genomic, biological, pathological, and clinical features and outcomes after systemic and locoregional treatments, outlining differences with recurrent metastatic breast cancer.
Review
The aim of this paper is to provide healthcare professionals involved in cancer pain management with a review of the relevant literature on the relationship between background cancer pain and breakthrough cancer
pain.
Original Research
This study was designed to evaluate the antiplatelet effect of deferiprone in patients with transfusion-dependent β-thalassaemia/Hb E at the dose of iron-chelation therapy. The results may provide a mechanistic insight in antiplatelet effects and support the benefit of deferiprone in the prevention of thrombotic events in β-thalassaemia.
Review
The authors review the current treatment landscape for patients with advanced non-small-cell lung cancers harbouring a KRAS G12C mutation, including PD-(L) 1-based therapies and direct KRAS inhibitors as well as sequential treatment options.
