Haematology and Oncology Archives - Page 14 of 20

Breakthroughs in hereditary angioedema management: a systematic review of approved drugs and those under research

Stefania Nicola MD, Giovanni Rolla MD, Luisa Brussino MD

Article Type

Review

Published

02 Oct 2019

This review focuses on the mechanisms of action, routes of administration, and efficacy of therapies for the rare genetic disorder hereditary angioedema.

Standard care and investigational drugs in the treatment of myelofibrosis

Daniela Barraco MD, Margherita Maffioli MD, Francesco Passamonti MD

Article Type

Review

Published

26 Sep 2019

This article reviews the therapeutic landscape in myelofibrosis, which has
significantly improved, and emerging drugs with different
target pathways, alone or in combination with ruxolitinib.
promising.

Palbociclib in metastatic breast cancer: current evidence and real-life data

Francesco Serra MD, Pietro Lapidari MD, Erica Quaquarini MD, Barbara Tagliaferri MD, Federico Sottotetti MD, Raffaella Palumbo MD, PhD

Article Type

Review

Published

16 Jul 2019

This review summarizes the background and latest evidence for the use of palbociclib, an oral, first-in-class, highly selective cyclin-dependent kinase 4/6 inhibitor, in advanced breast cancer, with a focus on some of the unanswered questions about the performance of this agent in clinical practice.

Immunotherapy in inoperable stage III non-small cell lung cancer: a review

Natasha A Jain MD, Gregory A Otterson MD

Article Type

Review

Published

17 Jun 2019

This article summarizes the current status and ongoing clinical trials incorporating immunotherapy into the management of inoperable stage III nonsmall cell lung cancer.

Second-line treatment options in hepatocellular carcinoma

Donatella Marino MD, Clizia Zichi MD, Marco Audisio MD, Elisa Sperti MD, Massimo Di Maio MD

Article Type

Review

Published

10 Apr 2019

This review discusses the evidence on second-line options for hepatocellular carcinoma, focusing on the latest results that are currently refining the treatment scenario.