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Efficacy of telbivudine with conditional tenofovir intensification in patients with chronic hepatitis B: results from the 2-year roadmap strategy

Authors: Teerha Piratvisuth, Piyawat Komolmit, Henry LY Chan, Tawesak Tanwandee, Wattana Sukeepaisarnjaroen, Mário G Pessoa, Eduardo Fassio, Suzane K Ono, Fernando Bessone, Jorge Daruich, Stefan Zeuzem, Michael Manns, Alkaz Uddin, Yuhong Dong, Aldo Trylesinski

Using data from a 2-year roadmap study, the authors concluded that telbivudine with add-on tenofovir was effective and well tolerated in patients with chronic hepatitis B, and that telbivudine was associated with an improvement in estimated glomerular filtration rate from baseline.