Sphingosine-1-phosphate receptor modulators in ulcerative colitis – a narrative review of current evidence and practical considerations

Anish J Kuriakose Kuzhiyanjal, Karishma Sethi-Arora, Gaurav B Nigam, Jimmy K Limdi

Article Type

Review

Published

This comprehensive review of Sphingosine-1-phosphate receptor modulators explores their mechanism of action, key clinical trial data, real-world insights, and an overview of their safety, including considerations for special populations and comparative effectiveness.

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Multimodal treatment of pineal metastasis from oesophageal adenocarcinoma

Francesca Rifaldi, Domiziana Alaimo, Anna Tortorella, Ilaria Imarisio, Anna Pagani, Salvatore Corallo, Paolo Pedrazzoli, Daniela Cicognini, Viola Custodi, Francesco Guerrini, Giannantonio Spena, Elisabetta Bonzano, Sara Colombo, Jacopo Viganò, Luca Ansaloni, Anna Gallotti, Alessandra Viglio, Francesco Serra

Article Type

Case Report

Published

The authors present a case of pineal metastasis from oesophageal adenocarcinoma managed by multimodal treatment and compare their observations with the available literature on this disease entity.

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Nurses’ perceptions on the usability of the Hyrimoz® Sensoready® autoinjector device

Charlotte Both, Elena Bachinskaya, Laura Rose, Carol M Antequera, Jessica R Allegretti

Article Type

Original Research

Published

This survey of gastroenterology nurses in the USA was designed to assess nurses’ perceptions regarding the Hyrimoz Sensoready pen, and the degree to which unique features might influence patient education when compared with the reference medicine autoinjector device, the Humira pen.

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Real-life effectiveness of FLOT in resectable gastric cancer: existing challenges

Francesco Serra, Federica Valerio, Paolo Pedrazzoli, Jacopo Viganò, Riccardo Caccialanza, Daniela Cicognini, Anna Pagani, Salvatore Corallo

Article Type

Original Research

Published

This article aims to demonstrate the real-life effectiveness of the fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT) regimen by comparing it with traditional chemotherapy regimens and aims to discover its strengths and weaknesses.

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