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Gastroenterology

Pharmacotherapy patterns in patients with chronic idiopathic constipation beginning treatment with linaclotide or lubiprostone in the United States

Authors: Arpita Nag PhD, Rebecca Bornheimer BA, Gerry Oster PhD

The objective of this retrospective cohort study was to examine patterns of use of linaclotide and lubiprostone, primarily focusing on duration of treatment and switching between agents, in patients with CIC, with and without IBS, using a large US health insurance claims database.

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Inflammatory bowel disease in patients with psoriasis treated with interleukin-17 inhibitors

Authors: Keira A Fieldhouse Bsc, Samantha Ukaibe BSc, Erika L Crowley BSc, MSc, Reena Khanna MD, MSc, FRCPC, Ashley O’Toole MD, MHSc, FRCPC, Melinda J Gooderham MD, MSc, FRCPC

This paper reviews all incident cases and exacerbations of IBD reported in the literature during widescale use of IL-17 inhibitors beyond the clinical trials.

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Vedolizumab in the treatment of inflammatory bowel disease: evolving paradigms

Authors: Benjamin Crooks MA MBBS, Tom Barnes MBBS BSc, Jimmy K Limdi FRCP FACG

This review brings together data reported on VDZ to date for treatment of inflammatory bowel diseases, comprising Crohn’s disease (CD) and ulcerative colitis (UC).

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Gastroesophageal reflux in children: an updated review

Authors: Alexander KC Leung MBBS, FRCPC, FRCP (UK and Irel), FRCPCH, FAAP, Kam Lun Hon MD, FAAP, FCCM

This review article provides an update on the current understanding, evaluation, and management of gastroesophageal reflux in children.

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New developments in ulcerative colitis: latest evidence on management, treatment, and maintenance

Authors: Kartikeya Tripathi MD, Joseph D Feuerstein MD

Ulcerative colitis is a chronic idiopathic inflammatory disorder that involves any part of the colon. The authors review the latest evidence on management, treatment, and maintenance.

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