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Tezepelumab for early-onset severe allergic asthma with persistent airflow limitation and small airway dysfunction: a treatable traits approach

Francesco Menzella, Claudio Sorino, Carlo Lombardi, Annamaria Bosi, Silvia Tonin, Lorenzo Corsi, Andrea Ballarin, Marcello Cottini

Article Type

Case Report & Review

Published

25 Sep 2025

This article describes the clinical and functional evolution of a young patient with severe early-onset allergic asthma with impaired respiratory function treated with the anti-thymic stromal lymphopoietin biologic agent tezepelumab.

Switching from multiple-inhaler triple therapy to single, extra fine-inhaler triple therapy in severe refractory asthma with EGPA: beyond control. Case report and review of the literature

Francesco Menzella, Marcello Cottini, Silvia Tonin, Lorenzo Corsi, Annamaria Bosi, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Matteo Tacconi, Carlo Lombardi

Article Type

Case Report & Review

Published

29 Apr 2025

This case report describes a 69-year-old male with severe, poorly controlled asthma who was diagnosed with eosinophilic granulomatosis with polyangiitis, it also presents a review of the literature on eosinophilic granulomatosis with polyangiitis and asthma management.