Pseudoprogression and improvement of quality of life in a patient with advanced endometrial cancer treated with immunotherapy: a case report

Valentina Tuninetti, Roberta Danese, Amedeo Calvo, Marco Bellero, Lavinia Bianco, Valentina Ariu, Maria Grazia Ruo Redda, Paola Campisi, Alessandra Bianco, Giovanni De Rosa, Massimo Petracchini, Giorgio Valabrega

Article Type

Case Report

Published

This article describes the case of a woman with deficient mismatch repair/microsatellite instability endometrial cancer who did not respond to first-line treatment with carboplatin and paclitaxel but had a high response to subsequent immunotherapy with dostarlimab.

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Real-world assessment of effectiveness and safety of filgotinib in 286 patients with ulcerative colitis in 9 UK centres

David Young, Sohail Rahmany, Deborah Taylor, Emma Davis, Michael Colwill, Sonia Kalyanji Mehta, Roisin Campbell, Karl Hazel, Karishma Sethi-Arora, Susan Ritchie, Ashley I Heinson, Helen Moyses, Keith Bodger, Emma Johnston, Lucy Hicks, Anjan Dhar, Jimmy Limdi, Rachel Cooney, John Paul Seenan, Kamal Patel, Alissa Walsh, Fraser Cummings

Article Type

Original Research

Published

This article reports the real-world
experience of 286 patients with ulcerative colitis treated with filgotinib as part of their routine clinical care in 9 UK centres.

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Evaluation of the criteria for renewal of LHRH agonists in patients with prostate cancer: results of the ANAREN Study

Jesús Calleja-Escudero, Víctor Barrondo, Andrés Rodriguez-Alonso, Francisco Gómez-Veiga, Joan Bestard, Antonio Gómez-Caamaño, Anne-Sophie Grandoulier, Maria Pérez-Sampietro, Venancio Chantada-Abal, Raúl Poza de Celis, on behalf of ANAREN Study Group

Article Type

Original Research

Published

This study aims to determine the percentage of patients whose initial luteinizing hormone-releasing hormone agonists prescription was renewed during follow-up, how many changed formulation and how their quality of life evolved.

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Understanding treatment goals and their application in clinical trial design for patients with Alzheimer disease and caregivers

David Gómez-Ulloa, M Chris Runken, Wilton I Rodriguez, Basilio Hernández, Montserrat Chivite, E Anne Davis, Paul Nisbet

Article Type

Original Research

Published

The goal of the present study was to survey patients with AD and caregivers to establish what they considered to be the most important treatment goals, thereby providing data for the systematic incorporation of these goals into Alzheimer disease clinical trials.

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