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Tag "Oncology"

Cutaneous side effects of molecularly targeted therapies for the treatment of solid tumors

Authors: Daniel I G Cubero MD, PhD, Beatrice Martinez Zugaib Abdalla MD, Jean Schoueri, Fabio Iazetti Lopes, Karine Corcione Turke, Jose Guzman MD, Auro Del Giglio MD, PhD, Carlos D’Apparecida Santos Machado Filho MD, PhD, Vanessa Salzano MD, Dolores Gonzalez Fabra MD

This article reviews the cutaneous side effects of main molecularly targeted cancer therapies for solid tumors.

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NEPA, a new fixed combination of netupitant and palonosetron, is a cost-effective intervention for the prevention of chemotherapy-induced nausea and vomiting in the UK

Authors: Helene Cawston, Francois Bourhis, Jennifer Eriksson, Pierfrancesco Ruffo, Paolo D’Agostino, Marco Turini, Lee Schwartzberg, Alistair McGuire

Despite study limitations (study setting, time horizon, utility measure), the results suggest NEPA is cost effective for preventing CINV associated with HEC and MEC in the UK.

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A new health-related quality of life instrument for leukemia: will it be widely adopted soon?

Authors: Junhua Yu, Joanna Cheung

Over the last decade, an increasing number of clinical trials in cancer research have been incorporating a health-related quality of life (HRQoL) instrument as part of their trial design. In this article the authors discuss the validity and usefulness of a new HRQoL instrument already in use in the United States.

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Targeting the metabolism of leukemia stem cells as a novel therapeutic strategy

Authors: Emmanuel A Ho, Neal M Davies

Unraveling our understanding of cancer stem cells and their role in the development and progression of acute myeloid leukemia could lead to improved outcomes.

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Novel therapeutic modalities and drug delivery in pancreatic cancer – an ongoing search for improved efficacy

Authors: Yuqing Zhang, Kei Satoh and Min Li

Pancreatic cancer is a challenging disease due to its high rates of resistance to traditional chemotherapy and radiotherapy. There has been little improvement in the prognosis of pancreatic cancer cases in the past decades, highlighting the need for more effective therapeutic approaches. This article summarizes current developments in targeted pancreatic cancer drug delivery, focusing on delivery systems, targets, and therapeutic agents.

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