Janus kinase inhibitors Archives

Home > Janus kinase inhibitors

Treatment of vitiligo with topical ruxolitinib: a narrative review

Gabriela Monteiro e Silva, Adam Mohamed, Cesar Ferreira, Tiago Torres

Article Type

Review

Published

15 Sep 2025

This narrative study aims to review and synthesize the current evidence on the safety, efficacy and therapeutic impact of topical ruxolitinib cream in vitiligo.

Tofacitinib and newer JAK inhibitors in inflammatory bowel disease – where we are and where we are going

Eleanor Liu, Nasar Aslam, Gaurav Nigam, Jimmy K Limdi

Article Type

Review

Published

11 Apr 2022

This narrative review summarizes the current literature regarding the mechanism of action of tofacitinib, data from registrational trials, emerging real-world evidence, and an overview of the most recent safety evidence. The authors explore evolving treatment paradigms and also present a brief overview of the next generation of JAK inhibitors in the pipeline.