endometrial cancer Archives - Drugs in Context

Advancing endometrial cancer treatment: exploring immunotherapy and tyrosine kinase inhibitors through clinical cases

Vanda Salutari

Article Type

Editorial

Published

24 Jun 2025

This editorial introduces the special series in Drugs in Context that explores treatment advancements for endometrial cancer through clinical case studies.

Overcoming disease progression in advanced endometrial cancer: a clinical case of sequential therapies

Amedeo Cefaliello, Angela Grieco, Roberto Buonaiuto, Valeria Forestieri

Article Type

Case Report

Published

24 Jun 2025

This article presents a case demonstrating the use of combination immunotherapy with pembrolizumab and lenvatinib in a patient with recurrent and metastatic endometrial cancer.

Pseudoprogression and improvement of quality of life in a patient with advanced endometrial cancer treated with immunotherapy: a case report

Valentina Tuninetti, Roberta Danese, Amedeo Calvo, Marco Bellero, Lavinia Bianco, Valentina Ariu, Maria Grazia Ruo Redda, Paola Campisi, Alessandra Bianco, Giovanni De Rosa, Massimo Petracchini, Giorgio Valabrega

Article Type

Case Report

Published

24 Jun 2025

This article describes the case of a woman with deficient mismatch repair/microsatellite instability endometrial cancer who did not respond to first-line treatment with carboplatin and paclitaxel but had a high response to subsequent immunotherapy with dostarlimab.

Long sustained response during second-line pembrolizumab plus lenvatinib in a patient with recurrent endometrial carcinoma: a case report

Laura Fabbri, Linda Galvani, Claudio Zamagni

Article Type

Case Report

Published

24 Jun 2025

A clinical case report with a favourable outcome aiming to compare the patient’s response and tolerability with efficacy and toxicity data reported in clinical studies.