Real-world effectiveness of a phlebotonic formulation combining diosmin, Ruscus, Melilotus and Vitis vinifera on symptoms and quality of life in patients with chronic venous and lymphatic disease: results from the VIVEMA Stasis observational study

Giampiero Avruscio, Carmen Tirritto, Sonia Ragazzo, Mario Mangrella, Roberto Piazza, Erica Tanasi

Article Type

Original Research

Published

The VIVEMA Stasis observational study was designed to evaluate the symptom burden, oedema reduction and quality of life in patients with chronic venous disease, lymphoedema and/or phlebolymphatic oedema treated with a phlebotonic formulation containing diosmin, Ruscus aculeatus, Melilotus officinalis and Vitis vinifera, combined with functional bandaging and elastic compression therapy.

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