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Tag "antiretroviral therapy"

HIV: how to manage heavily treatment-experienced patients

Authors: Stephanie Spivack, Stephen Pagkalinawan, Rafik Samuel, David E Koren

This narrative review provides an overview of the clinician approach to care, including diagnostics, approaches to regimen creation, relevant resources, and a broad array of
both currently available and upcoming antiretrovirals that may be used in regimens for heavily treatment-experienced patients.

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Experiences to date with the logistical management of long-acting cabotegravir and rilpivirine

Authors: Kamile Johnson, Mark T Sawkin

In this commentary, the authors describe experiences to date with acquiring, storing, handling, administering and billing for long-acting cabotegravir and rilpivirine through four scenarios, each of which have presented their own unique obstacles and learning curves.

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Pharmaceutical, clinical, and resistance information on doravirine, a novel non-nucleoside reverse transcriptase inhibitor for the treatment of HIV-1 infection

Authors: Hanh Thi Pham PhD, Meng A Xiao BSc, Miguel AV Principe BSc, Alexander Wong MD, Thibault Mesplède PhD

This review summarizes chemical, pharmacological, and clinical information about doravirine with an emphasis on drug resistance. The efficacy results from an early phase clinical trial evaluating doravirine in combination with islatravir are also provided.

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Oral oncolytic and antiretroviral therapy administration: dose adjustments, drug interactions, and other considerations for clinical use

Authors: Melissa E Badowski PharmD, MPH, Bradley Burton PharmD, Kristy M Shaeer PharmD, MPH, John Dicristofano BS, PharmD Candidate

This article evaluates existing literature through such means as drug databases and package inserts along with PubMed/Medline, Embase, and Google Scholar databases to develop a reference tool for providers to utilize when there is a decision to treat a patient with ART and oral oncolytic agents concurrently.

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Renal effects of non-tenofovir antiretroviral therapy in patients living with HIV

Authors: Milena M McLaughlin PharmD, MSc, Aimee J Guerrero BS, Andrew Merker PharmD

Reviews literature published regarding non-tenofovir antiretroviral agents causing renal adverse effects.

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