Toxic liver diseases consist of different kinds of liver injuries of different aetiologies, caused by endogenous factors such as dysmetabolic conditions – diabetes, dyslipidaemia, hypertension or obesity – or exogenous triggers such as drugs, alcohol or chemicals. Over the long term, such induced liver damage can progress to chronic liver disease. Unfortunately, limited treatment options are available. This case series shows clinical examples of patients diagnosed with liver damage due to comorbid conditions and multiple risk factors and successfully treated with silymarin to mitigate the altered liver functionality.

Silymarin and management of liver function in non-alcoholic steatohepatitis: a case report

Ahmed Hashem

Article Type

Case Report


This case report discusses daily treatment with silymarin and highlights moderate efficacy and a good safety profile in the management of non-alcoholic steatohepatitis (NASH) and liver function with no side-effects, supporting silymarin as a promising supplemental intervention that can normalize liver activity in non-alcoholic fatty liver disease and NASH.

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