Articles - Page 69 of 102 - Drugs in Context

Efficacy and safety of a GABAergic drug (Gamalate® B6): effects on behavior and cognition in young adults with borderline-to-mild intellectual developmental disabilities and ADHD

Ramón Novell MD, Susanna Esteba-Castillo PhD, Emili Rodriguez PhD

Article Type

Original Research

Published

23 Jan 2020

Gamalate B6 was evaluated in patients
with borderline intellectual functioning or mild intellectual
development disability and found to be effective and well tolerated for ADHD and challenging behavior.

Thyrotoxicosis after massive triiodothyronine (LT3) overdose: a coast-to-coast case series and review

Zhiheng H He MD, PhD, Yan Li MD, Nitin Trivedi MD, Sabrina Gill MD, James V Hennessey MD

Article Type

Review

Published

15 Jan 2020

Excessive exogenous thyroid hormone ingestion may lead to severe thyrotoxicosis and cause potential harm; this review of the literature suggests that thyroid hormone supplementation should not be used to alleviate nonspecific complaints in patients with normal endogenous thyroid function.

Combination checkpoint inhibitors for treatment of non-small-cell lung cancer: an update on dual anti-CTLA-4 and anti-PD-1/PD-L1 therapies

Sonam Puri MD, Michael Shafique MD

Article Type

Review

Published

13 Jan 2020

This review discusses the rationale, outcomes, and challenges of combination immune checkpoint blockade in non-small-cell lung cancer (NSCLC).

Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids

Luca Giacomelli PhD, Alessandra Moglia PharmD, Gianedoardo Losa PharmD, Pietro Quaglino MD

Article Type

Review

Published

09 Jan 2020

Clinical trials: their contribution to the efficiency of the clinical management of rheumatoid arthritis

Cristina P Alcañiz Escandell MD, José A Román Ivorra PhD

Article Type

Original Research

Published

23 Dec 2019

This article presents a descriptive analysis of theClinical Research Unit (CRU) at the Rheumatology Department in the University and Polytechnic Hospital La Fe (RD-UPH La Fe), Valencia (Spain), as well as an estimation of the economic impact of conducting clinical trials for the Spanish Health System in terms of avoided costs.