Articles

Health-related quality of life and clinical complexity of a real-life cohort of patients with advanced HR+/HER2– breast cancer treated with CDK4/6 inhibitors and endocrine therapy

Barbara Tagliaferri, Ludovica Mollica, Raffella Palumbo, Claudia Leli, Alberto Malovini, Matteo Terzaghi, Erica Quaquarini, Cristina Teragni, Stefano Maccarone, Andrea Premoli, Federico Sottotetti

Article Type

Original Research

Published

This real-life study investigated the link between clinical complexity and quality of life of patients with HR+/HER2– advanced breast cancer treated with CDK4/6 inhibitors.

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Treatment of the common cold with herbs used in Ayurveda and Jamu: monograph review and the science of ginger, liquorice, turmeric and peppermint

Retno S Wardani, Natalie Schellack, Tamlyn Govender, Abhay N Dhulap, Prapti Utami, Vinod Malve, Yong Chiat Wong

Article Type

Review

Published

This review aims to provide a better understanding of the traditional and modern perspectives on some of the herbal ingredients (ginger, liquorice, turmeric and peppermint) putatively used for common cold symptom management.

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Changes in nasal, pharyngeal and salivary secretory IgA levels in patients with COVID-19 and the possibility of correction of their secretion using combined intranasal and oral administration of a pharmaceutical containing antigens of opportunistic microorganisms

Mikhail Kostinov, Oksana Svitich, Alexander Chuchalin, Natalya Abramova, Valery Osiptsov, Ekaterina Khromova, Dmitry Pakhomov, Vitaly Tatevosov, Anna Vlasenko, Vilia Gainitdinova, Kirill Mashilov, Nadezhda Kryukova, Irina Baranova, Anton Kostinov

Article Type

Original Research

Published

This article aims to assess the secretion of SIgA in the nasal and pharyngeal compartments and saliva of patients with COVID-19 and to investigate the possibility and efficiency of correction of their secretion using combined intranasal and oral administration of a pharmaceutical containing antigens of opportunistic microorganisms.

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The future of clinical trials and drug development: 2050

Timothy C Hardman, Rob Aitchison, Richard Scaife, Jean Edwards, Gill Slater, on behalf of the Committee of the Pharmaceutical Contract Management Group

Article Type

Commentary

Published

This article discusses a workshop held at the 18th Annual Conference of the Pharmaceutical Contract Management Group (PCMG) in Krakow on 9th September 2022, which asked over 200 delegates what the clinical trial landscape would look like in 2050.

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