Articles

The convergent pathway of obstructive lung disease: the disease-modifying potential of dipeptidyl peptidase 1 inhibition in COPD, asthma and bronchiectasis overlap

Francesco Menzella, Marcello Cottini, Carlo Lombardi, Rory Chan

Article Type

Review

Published

This review synthesizes the pathophysiology and key aspects of bronchiectasis–COPD overlap syndrome and analyses the clinical evidence for brensocatib as the first potential disease-modifying therapy for this neutrophilic endotype designed to break the cycle.

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Optimizing care and quality indicators in the management of patients with acute ischaemic heart disease and atherothrombotic stroke: measuring to improve

José R González-Juanatey, Rafael Vázquez-García, Raquel Campuzano, José Luis Zamorano, María Isabel Egocheaga, Vicente Pascual Fuster, Ana Martín Sanz, Angels Pedragosa Vall, Jaime Masjuan

Article Type

Original Research

Published

The aim of this article is to develop an integrated organizational model for the care of acute ischaemic heart disease and atherothrombotic stroke, incorporating validated and measurable quality indicators to improve patient outcomes and care coordination.

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Role of a topical hydrogel (Dermatix® wound care gel) in acute and chronic wound management: a case series of real-world experiences and expert opinion from Asia

Chin Yen Lee, Elizabeth Wei Hsi Chang, Khong Yik Chew, Vilvkumaran Karupayah, Wildan Latief, Vi Anh Le, Dohar Tobing, Thi Phuong Thao Vu, Kean Chew Wong

Article Type

Case Series

Published

This article examines the effectiveness of Dermatix® Wound Care gel in acute and chronic wounds across various aetiologies, alone and in combination with other modalities, through a series of case studies.

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Apremilast in osteoarthritis: exploring its therapeutic mechanisms

Farzad Rafiei, Saina Sadeghipour, Seyed Mohammad Hosseini Marvast, Ali Mandegary, Hamidreza Soltani

Article Type

Review

Published

This review explores the mechanistic rationale and available evidence supporting the repurposing of apremilast in osteoarthritis, highlighting its potential to reduce pain and slow structural progression.

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Sphingosine-1-phosphate receptor modulators in ulcerative colitis – a narrative review of current evidence and practical considerations

Anish J Kuriakose Kuzhiyanjal, Karishma Sethi-Arora, Gaurav B Nigam, Jimmy K Limdi

Article Type

Review

Published

This comprehensive review of Sphingosine-1-phosphate receptor modulators explores their mechanism of action, key clinical trial data, real-world insights, and an overview of their safety, including considerations for special populations and comparative effectiveness.

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