Articles

Vericiguat in patients with heart failure and implantable cardioverter-defibrillator

Carlos Escobar, Jesús Saldaña, José Luis Merino, Rafael Peinado

Article Type

Original Research

Published

This article assesses the effectiveness and tolerability profile of vericiguat in clinical practice in patients with heart failure with reduced ejection fraction and an implantable cardioverter-defibrillator, with an emphasis on the emergence of ventricular arrhythmias.

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Lecanemab for mild Alzheimer disease – is there a way forward?

Rajesh R Tampi

Article Type

Editorial

Published

This Editorial reviews data on the efficacy and adverse effects of lecanemab amongst individuals with mild Alzheimer disease. The need for discussions regarding this medication as well as the importance of developing guidelines for use are also highlighted.

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Obinutuzumab in membranous nephropathy: a potential game-changer in treatment

Concetto Sessa, Dario Galeano, Luca Zanoli, Marco Delsante, Giovanni Maria Rossi, Walter Morale

Article Type

Review

Published

This articles reviews the pathophysiology of membranous nephropathy (MN), the mechanism of action of obinutuzumab, clinical data supporting its use and discusses its potential as a game changer in MN treatment.

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Real-life effectiveness of FLOT in resectable gastric cancer: existing challenges

Francesco Serra, Federica Valerio, Paolo Pedrazzoli, Jacopo Viganò, Riccardo Caccialanza, Daniela Cicognini, Anna Pagani, Salvatore Corallo

Article Type

Original Research

Published

This article aims to demonstrate the real-life effectiveness of the fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT) regimen by comparing it with traditional chemotherapy regimens and aims to discover its strengths and weaknesses.

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