Articles

Apremilast in osteoarthritis: exploring its therapeutic mechanisms

Farzad Rafiei, Saina Sadeghipour, Seyed Mohammad Hosseini Marvast, Ali Mandegary, Hamidreza Soltani

Article Type

Review

Published

This review explores the mechanistic rationale and available evidence supporting the repurposing of apremilast in osteoarthritis, highlighting its potential to reduce pain and slow structural progression.

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Sphingosine-1-phosphate receptor modulators in ulcerative colitis – a narrative review of current evidence and practical considerations

Anish J Kuriakose Kuzhiyanjal, Karishma Sethi-Arora, Gaurav B Nigam, Jimmy K Limdi

Article Type

Review

Published

This comprehensive review of Sphingosine-1-phosphate receptor modulators explores their mechanism of action, key clinical trial data, real-world insights, and an overview of their safety, including considerations for special populations and comparative effectiveness.

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Adjuvant abemaciclib in early-stage breast cancer: hypothesis-generating safety observations from a real-world cohort study

Federico Sottotetti, Simone Figini, Giulia Gambini, Gianpiero Rizzo, Giulia Chessa, Erica Quaquarini, Raffaella Palumbo, Lorenzo Perrone, Barbara Tagliaferri, Alessandra Ferrari, Catherine Klersy, Paolo Pedrazzoli, Laura Deborah Locati, Angioletta Lasagna

Article Type

Original Research

Published

This study aims to enhance comprehension of the clinical efficacy and safety of adjuvant abemaciclib in older women in a real-world setting compared with younger women.

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Holistic care in mild upper respiratory tract infections (MURTIs): an approach to individualized care management

Andrew Smith, Guillermo Estrada Riolobos, Marco Biagi, Andreas Michalsen, Laura Sadofsky, Ann Herzeel, Patrick Poucheret

Article Type

Review

Published

This article presents a patient-centred classification system for mild upper respiratory tract infections and proposes a 360° holistic care model that tailors effective, safe and suitable treatment to each individual’s symptoms and circumstances.

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