Articles

Patterns of treatment and outcomes of patients with metastatic HER2-low breast cancer treated with CDK4/6 inhibitors and hormone therapy

Federico Sottotetti, Barbara Tagliaferri, Gianpiero Rizzo, Raffaella Palumbo, Giulia Chessa, Chiara Raso, Lorenzo Perrone, Alberto Malovini, Valentina Tibollo, Laura Deborah Locati, Paolo Pedrazzoli, Angioletta Lasagna

Article Type

Original Research

Published

This study aims to investigate, through a retrospective approach and in a real-world setting, the activity and effectiveness of CDK4/6i as first-line or second-line treatment in a HR+/HER2-low population compared to matched patients with HR+/HER2-0 disease.

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Switching from multiple-inhaler triple therapy to single, extra fine-inhaler triple therapy in severe refractory asthma with EGPA: beyond control. Case report and review of the literature

Francesco Menzella, Marcello Cottini, Silvia Tonin, Lorenzo Corsi, Annamaria Bosi, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Matteo Tacconi, Carlo Lombardi

Article Type

Case Report & Review

Published

This case report describes a 69-year-old male with severe, poorly controlled asthma who was diagnosed with eosinophilic granulomatosis with polyangiitis, it also presents a review of the literature on eosinophilic granulomatosis with polyangiitis and asthma management.

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Anxiety disorders, PTSD and OCD: systematic review of approved psychiatric medications (2008–2024) and pipeline phase III medications

Emile Tadros, Shirley Keerthana, Samar Padder, Jayant Totlani, Drew Hirsch, Daniel N Kaidbay, Lorena Contreras, Aasim Naqvi, Samuel Miles, Krista Mercado, Ashley Meyer, Sabrina Renteria, Robert N Pechnick, Itai Danovitch, Waguih William IsHak

Article Type

Review

Published

By examining the mechanisms of action, indications, efficacy, dosing and adverse effects of psychiatic medications approved by the FDA, this review seeks to evaluate the progress and future directions in the pharmacological treatment of post-traumatic stress disorder and obsessive-compulsive
disorder.

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