Articles

N-acetylcysteine in paediatrics: a review of efficacy, safety and dosing strategies in respiratory care

Francesca Benedetti, Pierachille Santus

Article Type

Review

Published

This narrative review evaluates the efficacy and safety of N-acetylcysteine in paediatric acute and chronic respiratory diseases, synthesizing data from clinical trials, observational studies and real-world evidence, with a particular focus on optimizing dosing based on patient-specific characteristics.

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Multimodal treatment of pineal metastasis from oesophageal adenocarcinoma

Francesca Rifaldi, Domiziana Alaimo, Anna Tortorella, Ilaria Imarisio, Anna Pagani, Salvatore Corallo, Paolo Pedrazzoli, Daniela Cicognini, Viola Custodi, Francesco Guerrini, Giannantonio Spena, Elisabetta Bonzano, Sara Colombo, Jacopo Viganò, Luca Ansaloni, Anna Gallotti, Alessandra Viglio, Francesco Serra

Article Type

Case Report

Published

The authors present a case of pineal metastasis from oesophageal adenocarcinoma managed by multimodal treatment and compare their observations with the available literature on this disease entity.

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Place in therapy of key treatments for platinum-sensitive, relapsed, extensive-stage small cell lung cancer with a focus on lurbinectedin: a narrative review with case studies

Leonid Shunyakov, Firas B Badin, Judith Hafer, David König, Patrizia Froesch, Laurent Greillier

Article Type

Review

Published

This article reviews key second-line regimens recommended in major guidelines for treatment of patients with extensive-stage small cell lung cancer with platinum-sensitive relapse (chemotherapy-free interval ≥90 days), focusing on recent prospective clinical trials and post hoc analyses.

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