Articles - Drugs in Context

Platinum-induced ototoxicity and hearing impairment in children and adolescents

Alberto Romano, Giorgio Attinà, Palma Maurizi, Dario Talloa, Stefano Mastrangelo, Antonio Ruggiero

Article Type

Case Report

Published

05 Jun 2025

This narrative review aims to present the latest data on ototoxicity induced by platinum-based chemotherapy.

Real-world use of a hydrophilic curcumin-based oral formulation in the management of macular oedema: a collection of clinical experiences

Davide Allegrini, Giuseppe Covello, Alessandra Mancini, Antonino Mancini, Maura Mancini, Mary Romano, Aldo Vecchiarelli, Mario R Romano

Article Type

Real-World Study

Published

22 May 2025

This is a collection of clinical experiences exploring the real-world effectiveness of a hydrophilic curcuminbased oral formulation (CHC, Diabec) in the management of macular oedema across diverse retinal conditions

Upadacitinib for the treatment of radiographic axial spondyloarthritis — case series and review of the literature

Giuseppe Lopalco, Arianna D’Antonio, Maria Sole Chimenti, Florenzo Iannone

Article Type

Case Series & Review

Published

12 May 2025

Four case studies described here illustrate the effectiveness of upadacitinib in a range of real-world patients with axial spondyloarthritis.

Patterns of treatment and outcomes of patients with metastatic HER2-low breast cancer treated with CDK4/6 inhibitors and hormone therapy

Federico Sottotetti, Barbara Tagliaferri, Gianpiero Rizzo, Raffaella Palumbo, Giulia Chessa, Chiara Raso, Lorenzo Perrone, Alberto Malovini, Valentina Tibollo, Laura Deborah Locati, Paolo Pedrazzoli, Angioletta Lasagna

Article Type

Original Research

Published

07 May 2025

This study aims to investigate, through a retrospective approach and in a real-world setting, the activity and effectiveness of CDK4/6i as first-line or second-line treatment in a HR+/HER2-low population compared to matched patients with HR+/HER2-0 disease.

Switching from multiple-inhaler triple therapy to single, extra fine-inhaler triple therapy in severe refractory asthma with EGPA: beyond control. Case report and review of the literature

Francesco Menzella, Marcello Cottini, Silvia Tonin, Lorenzo Corsi, Annamaria Bosi, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Matteo Tacconi, Carlo Lombardi

Article Type

Case Report & Review

Published

29 Apr 2025

This case report describes a 69-year-old male with severe, poorly controlled asthma who was diagnosed with eosinophilic granulomatosis with polyangiitis, it also presents a review of the literature on eosinophilic granulomatosis with polyangiitis and asthma management.