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What was this study about? Acute ischemic heart disease (AIHD) and atherothrombotic stroke (AS) are serious cardiovascular conditions and major causes of death and long-term disability worldwide. These disorders share similar biological mechanisms, mainly driven by a process called atherothrombosis. Patient outcomes depend greatly on fast, high-quality emergency treatment and consistent long-term followup. However, the […]
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Role of a topical hydrogel (Dermatix® wound care gel) in acute and chronic wound management: a case series of real-world experiences and expert opinion from Asia This article presents real-world experience and expert opinions from Asian clinicians regarding the use of Dermatix® Wound Care (DWC) gel, an acidified hydrogel, in managing diverse acute and chronic […]
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Apremilast: mechanisms of its therapeutic effect in osteoarthritis Osteoarthritis (OA) is often mistakenly viewed as simple ‘wear-and-tear’ disease. However, it is now recognized as a complex, chronic disease involving low-grade inflammation, oxidative stress, and damage to cartilage and the underlying bone. This destructive cycle is driven by pro-inflammatory signals, primarily proteins called cytokines (like IL-17 […]
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What is ulcerative colitis and how is it treated? Ulcerative colitis is a chronic, relapsing and remitting condition that predominantly affects the large bowel. Some people with moderate or severely active ulcerative colitis require advanced therapy in the form of biological or small-molecule drugs (called advanced therapies) to maintain control of their symptoms. What advanced […]
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Background of the study Breast cancer is increasingly diagnosed in older women (aged ≥70 years), a group of patients not often included in clinical trials. Treatment guidelines, based mainly on younger patients, do not fully account for the complex needs of older people, like the presence of multiple health conditions (comorbidities) and overall frailty. Hormone […]