Women’s health Archives - Drugs in Context

Adjuvant abemaciclib in early-stage breast cancer: hypothesis-generating safety observations from a real-world cohort study

Federico Sottotetti, Simone Figini, Giulia Gambini, Gianpiero Rizzo, Giulia Chessa, Erica Quaquarini, Raffaella Palumbo, Lorenzo Perrone, Barbara Tagliaferri, Alessandra Ferrari, Catherine Klersy, Paolo Pedrazzoli, Laura Deborah Locati, Angioletta Lasagna

Article Type

Original Research

Published

11 Dec 2025

This study aims to enhance comprehension of the clinical efficacy and safety of adjuvant abemaciclib in older women in a real-world setting compared with younger women.

Management of refractory generalized myasthenia gravis with eculizumab during pregnancy and puerperium: a case report

Bedriye Karaman, Rasim Tunçel, Özgül Ekmekci, Nurten Uzun Adatepe, Nur Yüceyar

Article Type

Case Report

Published

01 Oct 2025

This case report describes a successful pregnancy in a patient who received eculizumab for refractory generalized myasthenia gravis that was difficult to manage during the pre-pregnancy period.

Properties and potentialities of hyaluronic acid and eXcellent Tridimensional Reticulation as a filling agent: a review

Vincent Wong, Martina Manni

Article Type

Review

Published

13 Aug 2025

This review summarizes the most relevant novelties in the field of HA fillers, focusing on the properties and potentialities of HA and XTR™ in the treatment of skin ageing.

Patterns of treatment and outcomes of patients with metastatic HER2-low breast cancer treated with CDK4/6 inhibitors and hormone therapy

Federico Sottotetti, Barbara Tagliaferri, Gianpiero Rizzo, Raffaella Palumbo, Giulia Chessa, Chiara Raso, Lorenzo Perrone, Alberto Malovini, Valentina Tibollo, Laura Deborah Locati, Paolo Pedrazzoli, Angioletta Lasagna

Article Type

Original Research

Published

07 May 2025

This study aims to investigate, through a retrospective approach and in a real-world setting, the activity and effectiveness of CDK4/6i as first-line or second-line treatment in a HR+/HER2-low population compared to matched patients with HR+/HER2-0 disease.

Effect of norethisterone dose and duration in the management of abnormal uterine bleeding: a narrative review and case report

Arun Madhab Boruah, Dibyendu Banerjee, Farendra Bhardwaj, Subash Mallya, Rajat Singal, Sugandha Sharma, Ashutosh Gautam

Article Type

Review

Published

04 Jul 2024

The present review summarizes the epidemiology and diagnosis of abnormal uterine bleeding, with a focus on the safety, efficacy and tolerability of norethisterone/norethisterone acetate in abnormal uterine bleeding management, as well as a case of abnormal uterine bleeding in a 40-year-old woman, who was treated with NETA tablets.