In this article, the authors explore basic sleep physiology, the mechanism of action for each class of hypnotic drugs and their clinical application. The potential pharmacologic sleep-inducing mechanisms of future hypnotics are also described and discussed.
This prospective, observational, non-interventional study conducted in six non-Western countries concludes that after 12 months of treatment, clinical and functional outcomes were improved in children and adolescents with attention deficit hyperactivity disorder (ADHD) who initiated and remained on their prescribed pharmacological monotherapy.
Major depressive disorder (MDD) is a significant public health concern and challenges health care providers to intervene with appropriate treatment. This review provides evidence that duloxetine 60 mg QD is effective for the treatment of adult patients with MDD in the short- and long-term phases of treatment. Duloxetine 60 mg QD also represents a viable choice of treatment for those patients with painful physical symptoms associated with MDD.
