Severe hypereosinophilia in a patient treated with dupilumab and shift to mepolizumab: the importance of multidisciplinary management. A case report and literature review

Sara Munari, Giulia Ciotti, Walter Cestaro, Lorenzo Corsi, Silvia Tonin, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Annamaria Bosi, Matteo Tacconi, Francesco Gialdini, Michele Gottardi, Francesco Menzella

Article Type

Review

Published

This article describes a case of severe hypereosinophilia in a patient with chronic rhinosinusitis with nasal polyps and asthma treated with dupilumab and a subsequent therapeutic shift to mepolizumab that led to maintenance of symptom control and concomitant normalization of blood eosinophil count.

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Bilastine for the treatment of allergic rhinoconjunctivitis and urticaria: results from an international Delphi study

Giorgio Walter Canonica, Piotr Kuna, Marcus Maurer, Ralph Mösges, Zoltan Novak, Nikolaus Papadopoulos, Pablo Rodriguez del Rio, the Delphi Study Group

Article Type

Original Research

Published

This study analyses available evidence supporting the use of bilastine amongst second-generation antihistamines for the symptomatic treatment of allergic rhinitis and urticaria in adults and children.

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Autoimmune findings in patients with silicosis in Spain

Coral González Fernández, Jose Antonio Ros Lucas, Maria Molina Molina, Juan Rigual Bobillo, Rogelio Alejandro García Montenegro, Raquel Fernández González, Ana Jaureguiza Oriol, Jose Abal Arca

Article Type

Original Research

Published

This articles aims to estimate the prevalence of silicosis with associated autoimmune findings in Spain and to assess the clinical and functional characteristics of affected patients.

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Use of immunomodulatory therapy as part of comprehensive treatment of non-severe community-acquired pneumonia and its long-term results

Mikhail P Kostinov, Vilia V Gainitdinova, Svetlana V Kazharova, Anna E Vlasenko, Vflentina B Polishchuk, Kirill V Mashilov

Article Type

Original Research

Published

This work aims to study the effectiveness of two different types of immunomodulators for the treatment of non-severe community-acquired pneumonia and assesses the long-term effects of the treatment conducted.

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