Article Type
Review
Published
This review article provides an update on the current understanding, evaluation, and management of gastroesophageal reflux in children.
Gastroenterology
Article Type
Review
Published
Ulcerative colitis is a chronic idiopathic inflammatory disorder that involves any part of the colon. The authors review the latest evidence on management, treatment, and maintenance.
Article Type
Review
Published
This review discusses the evidence on second-line options for hepatocellular carcinoma, focusing on the latest results that are currently refining the treatment scenario.
Article Type
Review
Published
Over the past ten years, sorafenib has been the only systemic agent approved for first-line treatment of patients with unresectable hepatocellular carcinoma (HCC) and in a second-line setting, most investigational drugs have failed to provide better survival outcomes than placebo. However, in 2016, data from the RESORCE trial, a phase 3 study evaluating regorafenib in HCC patients who experience disease progression after first-line treatment with sorafenib, have shown a 2.8-month median survival benefit over placebo (10.6 versus 7.8 months).
Article Type
Review
Published
This article summarizes the latest evidence and clinical implication in treatment of diverticular disease focusing either on the treatment of diverticulosis, symptomatic uncomplicated diverticular disease and acute diverticulitis together with the primary and secondary prevention of diverticulitis.