Dermatology Archives - Drugs in Context

Effectiveness of the antihistamine and anti-PAF effects of rupatadine in allergic diseases: off-label use in a case series study

Rita Aguiar, Rocío Concepción Albores-Arguijo, Ewa Cichocka-Jarosz, Joanna Jerzynska, Douglas P Mack

Article Type

Case Series

Published

09 Dec 2025

This case series shows the real-world effectiveness and safety of off-label rupatadine use in paediatric patients with clinically relevant complex allergy-related and dermatology-related conditions

Biologics and small molecules for psoriasis: current and future progress

Luca Potestio, Nello Tommasino, Michela D’Agostino, Valeria Esposito, Giuseppe Lauletta, Antonio Portarapillo, Matteo Megna

Article Type

Review

Published

20 Nov 2025

This narrative review explores new systemic therapies for psoriasis, including both approved and emerging biologics and small molecules, highlighting future directions in treatment.

JAK inhibitors for the treatment of palmoplantar pustulosis: a narrative review

Beatriz Henriques dos Santos, João Domingues, Marco Sousa, Tiago Torres

Article Type

Review

Published

22 Oct 2025

This narrative review evaluates current evidence on the efficacy and safety of JAK inhibitors in the treatment of palmoplantar pustulosis.

Treatment of vitiligo with topical ruxolitinib: a narrative review

Gabriela Monteiro e Silva, Adam Mohamed, Cesar Ferreira, Tiago Torres

Article Type

Review

Published

15 Sep 2025

This narrative study aims to review and synthesize the current evidence on the safety, efficacy and therapeutic impact of topical ruxolitinib cream in vitiligo.

Real-world analysis of IL-23 inhibitors in patients with moderate-to-severe psoriasis and early musculoskeletal symptoms

Annunziata Dattola, Nicoletta Bernardini, Jasmine Anedda, Laura Atzori, Claudio Bonifati, Pier Luigi Bruni, Domenico Giordano, Dario Graceffa, Elisa Molinelli, Gaia Moretta, Cristina Mugheddu, Annamaria Offidani, Gianluca Pagnanelli, Sabatino Pallotta, Manuela Papini, Severino Persechino, Antonio Giovanni Richetta, Ersilia Tolino, Federica Trovato, Giovanni Pellacani, Concetta Potenza

Article Type

Original Research

Published

08 Sep 2025

This article aims to evaluate the effect of IL-23 inhibitors on clinical outcomes and progression of PsA in patients with moderate-to-severe psoriasis and early musculoskeletal involvement.