The role of hypochlorous acid in the management of eye infections: a case series

Chiara Bertone, Antonella Mollicone, Stefano Russo, Paola Sasso, Romina Fasciani, Cinzia Riccardi, Mirella Lizzano, the ALI working group

Article Type

Case Series

Published

This case series presents and discusses real-life experiences with using an hypochlorous acid (HOCl) ophthalmic spray to manage eye infections, further characterizing the use of HOCl for ophthalmic applications.

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Corrigendum: The effect of azoximer bromide (Polyoxidonium®) in patients hospitalized with coronavirus disease (COVID-19): an open-label, multicentre, interventional clinical study

Sergey V Efimov, Natallia V Matsiyeuskaya, Olga V Boytsova, Lyudmila Yu Akhieva, Elena I Kvasova, Francisco Harrison, Yulia S Karpova, Anton Tikhonov, Nadezhda F Khomyakova, Tim Hardman, Jean-François Rossi

Article Type

Corrigendum

Published

The authors wish to make the following corrections to their article: Efimov SV, Matsiyeuskaya NV, Boytsova OV, et al. Corrigendum: The effect of azoximer bromide (Polyoxidonium®) in patients hospitalized with coronavirus disease (COVID-19): an open-label, multicentre, interventional clinical study. Drugs in Context 2021; 10: 2021-11-1. DOI: 10.7573/dic.2020-11-1

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The effect of azoximer bromide (Polyoxidonium®) in patients hospitalized with coronavirus disease (COVID-19): an open-label, multicentre, interventional clinical study

Sergey V Efimov, Natallia V Matsiyeuskaya, Olga V Boytsova, Lyudmila Yu Akhieva, Elena I Kvasova, Francisco Harrison, Yulia S Karpova, Anton Tikhonov, Nadezhda F Khomyakova, Tim Hardman, Jean-François Rossi

Article Type

Original Research

Published

The aim of this study was to observe the safety and efficacy of AZB as an addition to the complex treatment of patients hospitalized with COVID-19. This study is the first exploratory
use of AZB in patients with COVID-19.

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Severe refractory asthma: current treatment options and ongoing research

Francesco Menzella MD, Francesca Bertolini MSc, PhD, Mirella Biava MSc, Carla Galeone MSc, Chiara Scelfo MD, Marco Caminati MD

Article Type

Review

Published

In this review, the different biological options available for the treatment of severe refractory asthma, their mechanism of action, and the overlapping aspects of their usage in clinical practice are discussed.

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Repurposing existing drugs for cardiovascular risk management: a focus on methotrexate

Arduino A Mangoni MD, PhD, FRCP, FRACP, Sara Tommasi PhD, Angelo Zinellu PhD, Salvatore Sotgia MSc, Ciriaco Carru PhD, Matteo Piga MD, Gian Luca Erre MD

Article Type

Review

Published

This review discusses the current challenges in the management of cardiovascular disease; the available evidence on the effects of methotrexate on inflammation, blood pressure, and surrogate markers of arterial function; suggestions for future research directions; and practical considerations with the use of methotrexate in this context.

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