Plain Language Summary
What is N-acetylcysteine? N-acetylcysteine (NAC) is a medication often used to help people with lung conditions that involve thick mucus such as bronchitis, pneumonia and cystic fibrosis. It works by thinning mucus, making it easier to clear from the lungs. It also has other helpful effects, for example, it can reduce inflammation, protect lung tissue […]
Plain Language Summary
Background About 2 out of 3 individuals who present to a doctor with symptoms of small cell lung cancer (SCLC) will be diagnosed with advanced disease. Standard treatment with platinum-etoposide plus atezolizumab or durvalumab is highly effective; however, virtually all patients who respond to this primary (first-line) treatment will become resistant to platinum and relapse. […]
Plain Language Summary
Palmoplantar pustulosis (PPP) is a chronic, inflammatory skin disease characterized by sterile pustules on the palms and/or soles. These lesions often fissure, causing significant pain, functional impairment and reduced quality of life. The disease predominantly affects women in middle age and is strongly associated with smoking. PPP is challenging to treat as it often responds […]
Plain Language Summary
This article presents a case study about a young woman with a severe form of myasthenia gravis (MG), a disease that causes muscle weakness. Her condition was so severe that it was considered ‘refractory’, meaning that it didn’t respond well to standard treatments. The patient had tried several medications, but her symptoms, including difficulty walking […]
Plain Language Summary
Case summary: tezepelumab for allergic asthma This case report details the successful treatment of a young woman with severe allergic asthma using a new medication called tezepelumab. Patient’s condition and treatment challenge The patient was an 18-year-old woman with a long history of severe asthma that was not well-controlled, even with advanced inhaler therapy. A […]