Tardive dyskinesia in patients treated with atypical antipsychotics: case series and brief review of etiologic and treatment considerations

Tardive dyskinesia in patients treated with atypical antipsychotics: case series and brief review of etiologic and treatment considerations

Article Page

Tardive dyskinesia (TD) is a disfiguring side-effect of antipsychotic medications that is potentially irreversible in affected patients. Newer atypical antipsychotics are felt by many to have a lower risk of TD. As a result, many clinicians may have developed a false sense of security when prescribing these medications. We report five cases of patients taking atypical antipsychotics who developed TD, review the risk of TD, its potential etiologic mechanisms, and treatment options available. The goal of this paper is to alert the reader to continue to be diligent in obtaining informed consent and monitoring for the onset of TD in patients taking atypical antipsychotics.

Keywords: tardive dyskinesia, antipsychotic agents, dopamine receptor antagonists

Citation: Kim J, MacMaster E, Schwartz TL. Tardive dyskinesia in patients treated with atypical antipsychotics: case series and brief review of etiologic
and treatment considerations. Drugs in Context 2014;3:212259. doi: 10.7573/dic.212259

Provenance: Submitted; externally peer reviewed

Dates: Submitted: 11 December 2013; 
Accepted, subject to peer review: 12 December 2013
; Revised manuscript submitted: 19 March 2014
; Published: 9 April 2014

Copyright: © 2014 Kim J, MacMaster E, Schwartz TL. This is an open-access article distributed under the terms of the Creative Commons Attribution License Deed CC BY 3.0 which allows anyone to copy, distribute, transmit and adapt the article provided it is properly attributed in the manner specified below.

Correct attribution: Copyright © 2014 Kim J, MacMaster E, Schwartz TL. http://dx.doi.org/10.7573/dic.212259. Published by Drugs in Context under Creative Commons Attribution License Deed CC BY 3.0.

Correspondence: Thomas Schwartz, MD, Professor of Psychiatry, Department of Psychiatry, SUNY Upstate Medical University, 713 Harrison St, Syracuse NY 13210, USA

Email: schwartt@upstate.edu

Download free full text PDF

Resources