Prevention of post-contrast kidney injury in patients with cancer

Emanuele Grassedonio, Lorena Incorvaia, Marco Guarneri, Fabio Guagnini, Massimo Midiri

Article Type

Review

Published

This article aims to review the literature on mechanisms of post-contrast acute kidney injury, risk factors and available strategies to control the risk in patients with cancer and to report the authors’ experience with managing post-contrast acute kidney injury risk in oncology.

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Tackling the clinical complexity of breast cancer

Marco Vincenzo Lenti, Federico Sottotetti, Gino Roberto Corazza

Article Type

Commentary

Published

The authors provide their view about the possible factors triggering clinical complexity, the key issues of clinical complexity and the related unmet needs in breast cancer.

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Oral oncolytic and antiretroviral therapy administration: dose adjustments, drug interactions, and other considerations for clinical use

Melissa E Badowski PharmD, MPH, Bradley Burton PharmD, Kristy M Shaeer PharmD, MPH, John Dicristofano BS, PharmD Candidate

Article Type

Review

Published

This article evaluates existing literature through such means as drug databases and package inserts along with PubMed/Medline, Embase, and Google Scholar databases to develop a reference tool for providers to utilize when there is a decision to treat a patient with ART and oral oncolytic agents concurrently.

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Approving cancer treatments based on endpoints other than overall survival: an analysis of historical data using the PACE Continuous Innovation Indicators™ (CII)

Neon Brooks, Mario Campone, Silvia Paddock, Scott Shortenhaus, David Grainger, Jacqueline Zummo, Samuel Thomas, Rose Li

Article Type

Original Research

Published

This article examines the relationship between U.S. Food and Drug Administration (FDA) approval and the publication of OS evidence to understand better the risks and benefits of delaying approval until OS evidence is available.

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