Latest research

Novel therapeutic modalities and drug delivery in pancreatic cancer – an ongoing search for improved efficacy

Novel therapeutic modalities and drug delivery in pancreatic cancer – an ongoing search for improved efficacy

Pancreatic cancer is a challenging disease due to its high rates of resistance to traditional chemotherapy and radiotherapy. There has been little improvement in the prognosis of pancreatic cancer cases in the past decades, highlighting the need for more effective therapeutic approaches. This article summarizes current developments in targeted pancreatic cancer drug delivery, focusing on delivery systems, targets, and therapeutic agents.

Is ‘GOLD’ standard for the management of COPD in clinical practice?

Is ‘GOLD’ standard for the management of COPD in clinical practice?

Primary therapy for chronic obstructive pulmonary disease (COPD) is the removal of the toxic agent (in most cases, tobacco smoke). Additional therapy includes bronchodilators. Inhaled corticosteroids and long-acting bronchodilators can be used to prevent and reduce the risk of exacerbations. COPD is a systemic disease and often requires therapy of its protean-associated morbidities from depression to osteoporosis and muscle wasting. Despite pessimism from some, COPD is treatable.

Metastatic melanoma – a review of current and future drugs

Metastatic melanoma – a review of current and future drugs

A systematic search of literature was conducted, and studies providing data on the effectiveness of current and/or future drugs used in the treatment of metastatic melanoma were selected for review. This review discusses the advantages and limitations of these agents, evaluating past, current and future clinical trials designed to overcome such limitations.

A specialist publication platform for research and comment on all aspects of gastroenterology

A specialist publication platform for research and comment on all aspects of gastroenterology

Drugs in Context Gastroenterology publishes rigorously peer reviewed, original research and journalistic articles on all aspects of the management of diseases of the gastrointestinal tract, quickly, continuously and open-access. All articles published in Drugs in Context Gastroenterology are indexed in PubMed, Scopus and Embase.

A specialist publication platform for research and comment on all aspects of dermatology

A specialist publication platform for research and comment on all aspects of dermatology

Drugs in Context Dermatology publishes rigorously peer reviewed, original research and journalistic articles on all aspects of the diagnosis and management of dermatological conditions, quickly, continuously and open-access. All articles published in Drugs in Context Dermatology are indexed in PubMed, Scopus and Embase.