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Analgesia and anaesthesiology

Administration of intravenous morphine for acute pain in the emergency department inflicts an economic burden in Europe

Authors: Montserrat Casamayor MD, PhD, Karen DiDonato MSN, RN, Marc Hennebert MBA, MS, Luca Brazzi MD, PhD, Gregor Prosen MD, FEBEM

This article estimates the burden of IV administration of morphine in the five key European countries (EU5) using a micro-costing approach.

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Suvorexant for insomnia in older adults: a perspective review

Authors: Rajesh R Tampi, Geetha Manikkara, Silpa Balachandran, Piyush Taparia, Stephanie Hrisko, Shilpa Srinivasan, Deena J Tampi

This review identifies published randomized control trials that evaluate the efficacy and tolerability of suvorexant for the treatment of insomnia among older adults.

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Clinical and cost outcomes from different hyaluronic acid treatments in patients with knee osteoarthritis: evidence from a US health plan claims database

Authors: Vinod Dasa, Mitch DeKoven, Kainan Sun, Allan Scott, Sooyeol Lim

Intra-articular injection of hyaluronic acid (HA) for knee osteoarthritis (OA) effectively reduces pain and delays total knee replacement (TKR) surgery; however, little is known about relative differences in clinical and cost outcomes among different HA products. In this study, the authors conclude that analysis of administrative claims data provides real-world evidence that meaningful differences exist among some HA products in disease-specific cost and time to knee replacement surgery.

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